主动脉内球囊反搏在严重冠心病中的临床应用  

The clinical application of intra-aortic balloon pumping in treating serious coronary heart disease

作　　者：张国培[1] 张亚军[1] 宋建祥[1] 邹其银[1] 

机构地区：[1]东南大学医学院附属盐城医院心脏病诊治中心,江苏省盐城224001

出　　处：《中国基层医药》2010年第23期3198-3199,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 探讨主动脉内球囊反搏（IABP）在严重冠心病中的应用效果. 方法 回顾性分析应用IABP治疗的19例严重冠心病患者,比较使用IABP治疗前后平均动脉压的变化.19例患者分为两组,单纯IABP组6例,IABP联合血运重建（溶栓/冠状动脉介入治疗/冠状动脉旁路移植术）组13例,比较两组的院内病死率. 结果 IABP床边操作成功率100%,无相关并发症发生.IABP治疗有效率89.5%.IABP使用30 min后,患者的平均动脉压由（52.1±18.4）mm Hg上升到（78.3±20.8）mm Hg（P＜0.01）.单纯IABP组与联合血运重建组院内病死率比较（83.3%比7.7%,P＜0.01）. 结论 IABP治疗严重冠心病安全、有效.联合血运重建治疗可以降低严重冠心病患者的院内病死率.Objective To evaluate the effect of intra-aortic balloon pumping（IABP）in treating serious coronary heart disease. Methods A retrospective analysis was performed on 19 patients who suffered from serious coronary heart disease and accepted IABP therapy,the differences of mean arterial pressure before and after treatment were compared.In order to compare the in-hospital mortality,the patients were divided into 2 groups：6 of 19 patients accepted single IABP therapy,13 of 19 patients attempted IABP and revascularization（thrombolytic/percutaneous coronary intervention/coronary artery bypass graft）therapy. Results Bedside success rate of IABP operation was 100%without complication.Effective rate was 89.5%（17/19）,2 patients who were irreversible phase of cardiogenic shock,were an ineffective treatment.The patient＇s mean arterial pressure increased from（52.1 ± 18.4）mm Hg to（78.3 20.8）mm Hg after using IA BP for 30 minutes（P〈0.01）.The in-hospital mortality was significantly lower in patients received revascularization therapy in addition to IABP compared with patients who had IABP support alone 7.7% vs 83.3%（P〈0.01）. Conclusion IABP in treating serious coronary heart disease was safe and effective.IABP treatment before irreversible phase of shock and revascularization therapy following IABP are the key to decrease in-hospital mortality.

关 键 词：主动脉内气囊泵 治疗学 

分 类 号：R541[医药卫生—心血管疾病]