80岁以上老年人单纯收缩期高血压与颈动脉硬度  

The Relationship Between Carotid Artery Stiffness and Isolated Systolic Hypertension in Patients at 80 Years or Elder

作　　者：诸葛铭宁[1] 蔡玉琴[1] 斯重阳[1] 马淑平[1] 

机构地区：[1]河北省人民医院高血压研究室,河北省石家庄市050051

出　　处：《中国循环杂志》2010年第6期453-455,共3页Chinese Circulation Journal

摘　　要：目的:研究80岁以上高龄老年人单纯性收缩期高血压(ISH)与颈动脉僵硬度的关系。方法:采用高分辨率超声仪对80岁以上高龄老年人单纯收缩期高血压患者25例(单纯收缩期高血压组)、收缩期/舒张期均高的高血压患者24例(收缩期/舒张期高血压组)及正常血压者20例(正常对照组)进行检测,测量其颈动脉收缩期和舒张期内径,并计算颈动脉紧张度、扩张性和僵硬度,而后对3组之间进行差异显著性比较及相关因素分析。结果:颈动脉紧张度在单纯收缩期高血压组低于收缩期/舒张期高血压组(P<0.05),与正常对照组比较差异无统计学意义(P>0.05)。颈动脉扩张性在单纯收缩期高血压组和收缩期/舒张期高血压组明显低于正常对照组(P<0.01);颈动脉僵硬度在单纯收缩期高血压组明显高于正常对照组和收缩期/舒张期高血压组(P<0.01);差异均有统计学意义。结论:80岁以上高龄老年人单纯性收缩期高血压患者颈动脉僵硬度增加,颈动脉扩张性降低,临床上应重点关注对单纯性收缩期高血压患者的检查和治疗。Objective：To explore the relationship between the carotid artery stiffness and isolated systolic hypertension（ISH） in patients at 80 years or elder.Methods：A total of 49 octogenarian patients were divided into two groups,ISH group,n=25,systolic and diastolic phase hypertension（S/DH） group,n=24;and Control group,n=20,the subjects had normal blood pressure with the matched age,gender and body weight.The carotid diameter was measured by Doppler ultrasonography,arterial strain（AS）,arterial distensibility（AD） and arterial stiffness（ASt） were calculated and compared in different groups.Results：The AS was lower in ISH group than that in S/DH group,P0.05,while the AS in ISH group was similar to that in Control group.The AD in both ISH group and S/DH group was obviously decreased than that in Control group,P0.01.The ASt was significantly increased in ISH group than that in S/DH group and in Control group（P0.01）.Conclusion：Octogenarian ISH patients has increased ASt and decreased AD,more attention should be emphasized for those patients in clinical examination and treatment.

关 键 词：高血压 颈动脉疾病 高龄老年人 超声检查 

分 类 号：R541[医药卫生—心血管疾病]