基于分形理论的婴幼儿正常脑发育医学图像量化分析  

Quantitative Analysis Method Based on Fractal Theory for Medical Imaging of Normal Brain Development in Infants

作　　者：李鹤虹[1,2] 罗良平[1] 黄力[1] 

机构地区：[1]暨南大学附属第一医院医学影像中心,广州510632 [2]广州市妇女儿童医疗中心CT室,广州510120

出　　处：《生物医学工程学杂志》2011年第1期18-21,共4页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(30772303);广东省社会发展科技计划项目资助(2010B031600104)

摘　　要：对具备正常运动功能和智力发育水平的健康婴幼儿158例进行脑发育过程的分形机制研究和量化分析,显示新生儿期正常脑分形维数范围分布在1.88～1.90之间,平均1.8913±0.0064;1～12月龄幼儿稳定在1.89～1.90之间,均值为1.8927±0.0045;1～2岁儿童分形维数稳定在1.86～1.90,均值为1.8863±0.0085;2～3岁幼儿分形维数稳定在1.88～1.91之间,均值为1.8958±0.0083,单因素方差检验显示不同年龄组间具备统计学显著性差异(F=8.947,P<0.001),正常婴幼儿脑实质分形维数范围稳定在1.86～1.91之间,总体上保持了非常稳定的状态,代表婴幼儿脑发育存在混沌的"吸引子"形式,具备分形特性。The present paper is aimed to study the fractal spectrum of the cerebral computerized tomography in 158 normal infants of different age groups,based on the calculation of chaotic theory.The distribution range of neonatal period was 1.88-1.90（mean=1.8913±0.0064）;It reached a stable condition at the level of 1.89-1.90 during 1-12months old（mean=1.8927±0.0045）;The normal range of 1-2 years old infants was 1.86-1.90（mean=1.8863±0.0085）;It kept the invariance of the quantitative value among 1.88-1.91（mean=1.8958±0.0083） during 2-3 years of age.ANOVA indicated there＇s no significan difference between boys and girls（F=0.243,P0.05）,but the difference of age groups was significant（F=8.947,P0.001）.The fractal dimension of cerebral computerized tomography in normal infants computed by box methods was maintained at an efficient stability from 1.86 to 1.91.It indicated that there exit some attractor modes in pediatric brain development.

关 键 词：分形 婴幼儿 定量化 分析 发育 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]