紫外分光光度法测定烟酸微丸中烟酸的含量  

Determination of Content of Nicotinic acid Micropellets using ultraviolet Spectrophotometry

作　　者：李桂华 付瑾[2] 张华[2] 江发寿[2] 吴增宝[2] 陈文[2] 

机构地区：[1]新疆玛纳斯佳园医院,新疆玛纳斯832200 [2]石河子大学药学院新疆特种植物药资源省部共建教育部重点实验室,新疆石河子832002

出　　处：《农垦医学》2010年第4期299-301,共3页Journal of Nongken Medicine

基　　金：新疆兵团医药卫生专项(05GG39)

摘　　要：目的：测定烟酸微丸中烟酸的含量。方法：采用离心造粒法制备烟酸含药微丸,利用紫外分光光度法建立烟酸的含量测定方法。结果：在2.0-20.0μg.m l^-1范围内,线性关系良好,平均回收率为98.5%,RSD%小于2.5%,烟酸微丸的含药量为70.6%。结论：采用紫外分光光度法测定烟酸含量方法准确、操作简便,快速,重现性好。Objective：To determine the content of nicotinic acid micropellets.Methods：Centrifugal granulation method was used to prepare nicotinic acid micropellets,the nicotinic acid was determined by UV method.Results：Nicotinic acid showed good linear correlation within a concentration range of 2.0~20.0 μg·mL-1 with RSD%〈2%.Average recovery rate was 98.5%,and the content of nicotine acid micropellets was 70.6 %.Conclusion：The UV Spectrophotometry used for determining the content of nicotinic acid micropellets yielded was accurate,simple,quick and reproducible.

关 键 词：烟酸 离心造粒法 紫外分光光度法 含量测定 

分 类 号：R927.2[医药卫生—药学]