超临界CO_2萃取麦冬中高异黄酮类物质的工艺研究  

Study on Supercritical CO2 Extraction Technology of Homoisoflavone from Radix Ophiopogonis

作　　者：曾品涛[1] 郑一敏[1] 胥秀英[1] 傅善权[1] 胡杨[1] 李杰[1] 

机构地区：[1]重庆理工大学药学与生物工程学院,重庆400050

出　　处：《中国药业》2010年第24期45-46,共2页China Pharmaceuticals

摘　　要：目的确定超临界CO2萃取麦冬中高异黄酮类物质的最佳工艺条件。方法通过单因素试验及正交试验考察最佳萃取工艺条件,并测定萃取物中总高异黄酮含量。结果最佳工艺条件是萃取温度55℃,萃取压力20MPa,萃取时间120min,夹带剂用量2.0mL/mg。结论超临界CO2萃取麦冬中高异黄酮类物质萃取率高、工艺简单、重现性好。Objective To study the optimum supercritical CO2 extraction technology of homoisoflavone from Radix Ophiopogonis.Methods The single-factor test and orthogonal tests were adopted to optimize the extraction process using the content of homoisoflavone as indicator.Results The optimal extraction conditions were the temperature at 55 ℃,the pressure at 20 MPa,the extraction time for 2 h and the entrainer volume for 2.0 mL/mg.Conclusion This technology is characterized by high extraction yield,simplicity and good reproducibility.

关 键 词：高异黄酮 麦冬 超临界二氧化碳萃取 正交试验 

分 类 号：TQ461[化学工程—制药化工] R284.2[医药卫生—中药学]