儿童哮喘1952例吸入变应原皮肤点刺结果分析  

Skin prick analysis of aspiration allergens 1952 cases of children with asthma

作　　者：艾涛[1] 罗荣华[1] 吴英[1] 樊映红[1] 王次林[1] 廖惠玲[1] 杨亚静[1] 

机构地区：[1]成都市儿童医院,四川成都610017

出　　处：《四川医学》2010年第12期1742-1744,共3页Sichuan Medical Journal

基　　金：四川省卫生厅资助项目(编号:070337)

摘　　要：目的了解成都地区哮喘患儿常见吸入性过敏原的过敏情况;探讨不同年龄组之间变应原阳性率差异。方法选择我院2008年1月～2010年1月呼吸专科门诊诊断为支气管哮喘的患儿1952例为研究对象,采用丹麦ALK-ABELLO公司提供的13种标准化变应原皮肤点刺液进行试验。结果变应原点刺试验总阳性检出率为73.43%(1434/1952),其中屋尘螨952例(48.77%),粉尘螨930例(47.64%)等阳性率较高,其次为:热带螨774例(39.65%),德国小蠊608例(31.15%),美洲大蠊598例(30.64%),猫毛440例(22.54%),狗毛370例(18.96%),艾蒿247例(12.64%),豚草174例(8.91%);在吸入性过敏原比较中高龄组变应原阳性率均高于低年龄组,差异有统计学意义(P<0.001)。结论尘螨是成都地区儿童哮喘的主要吸入性过敏原;不同年龄段的儿童哮喘其过敏原的阳性率是不同的。Objective To find out the anaphylactic status of common aspiration allergens of children with asthma in Chengdu area,and investigate the discrepancies of positive incidences of allergens among different age groups. Methods 1952 cases of children with bronchial asthma are selected for the study objectives and they are diagnosed by respiration out-patient in our hospital over the period from January 2008 to January 2010.Tests are carried out by using 13 kinds of standardized allergenic skin prick liquid provided by ALK-ABELL0 Company Denmark.Results The total positive detectable rate in the allergenic prick tests is 73.43% （1434/1952）among which the top two positive incidences are dermatophagoides pteronyssinuses（952 cases）and dermatophagoides farinaes（930 cases）,accounting respectively for 48.77%and 47.64%,respectively.In addition,there are 774 cases of blomia tropicalises,608 cases of blattella germanicas,598 cases of periplaneta americanas,440 cases of cat hair,370 cases of dog hair,247 cases of biennial wormwoods and 174 cases of ragweeds,accounting respectively for 39.65%,31.15%, 30.64%,22.54%,18.96%,12.64%and 8.91%.When making aspiration allergen comparisons,the positive incidences of allergens in older age group are higher than those in younger age group. The discrepancy is statistically significant（P0.001）. Conclusion Dust mite is the main aspiration allergen of children with asthma in Chengdu area.The positive incidences of allergens are different for children of different ages with asthma.

关 键 词：儿童哮喘 吸入变应原 皮肤点刺试验 

分 类 号：R725.6[医药卫生—儿科]