新疆阿魏种子化学成分的研究(Ⅰ)  

Chemical Constituents from the Seeds of Ferula Sinkiangensis

作　　者：王月娥[1,2] 斯建勇 李晓瑾[1,2] 姜林[1,3] 朱军[2] 

机构地区：[1]新疆医科大学中医学院,新疆乌鲁木齐830054 [2]新疆维吾尔自治区中药民族药研究所,新疆乌鲁木齐830002 [3]新疆医科大学中医学院中药制剂教研室,新疆乌鲁木齐830054

出　　处：《中国现代中药》2011年第1期26-28,共3页Modern Chinese Medicine

基　　金：国家自然科学基金项目(81060265)

摘　　要：目的:分析新疆阿魏种子的化学成分。方法:通过硅胶柱色谱、Sephadex LH-20柱色谱、重结晶等技术分离纯化,根据理化性质和光谱数据进行结构鉴定。结果:从新疆阿魏种子中分离得到6个化合物,分别鉴定为豆甾醇(1),豆甾醇-3-O-葡萄糖苷(2),柯拉多宁(3)(colladonin),Sinkianone(4),阿魏酸(5),7-羟基香豆素(6)。结论:化合物1、2、3、5、6为首次从该植物中分离得到。Objective： The chemical constituents from the seeds of Ferula sinkiangensis were studied. Methods： The constituents were isolated and purified by column chromatographies and their structures were identified by physico-chemical properties as well as spectral data. Results： Six compounds were isolated from the seeds of F. sinkiangensis and their structures were elucidated as stigmasterol （ 1 ）, stigmasterol-3 -O-glucoside （ 2 ）, colladonin （ 3 ）, siknianone （4）, ferulic acid （ 5 ）, 7 -hydroxycoumarin （ 6 ）. Conclusion： Compounds 1,2,3,5,6 were isolated from the seeds of F. sinkiangensis for the first time .

关 键 词：新疆阿魏 种子 化学成分 

分 类 号：R962[医药卫生—药理学]