宫内节育器不良事件发生率与地区经济水平的关系研究  

Regional Economic Levels and Adverse Events Linked to Intrauterine Devices

作　　者：高霑[1] 李玲[1] 李瑛[2] 李幼平[1] 文进[1] 王莉[1] 

机构地区：[1]四川大学华西医院中国循证医学中心,成都610041 [2]江苏省计划生育科学技术研究所,南京210036

出　　处：《中国循证医学杂志》2011年第2期138-142,共5页Chinese Journal of Evidence-based Medicine

基　　金："十一五"国家科技支撑计划课题"避孕药具上市后监测和风险再评价研究"(编号:2006BAI15B07)

摘　　要：目的探索宫内节育器(IUD)不良事件发生率与地区经济水平的关系,为促进计划生育工作及提高服务水平提供决策依据。方法采用回顾性研究方法,以乡镇为单位统计居民人均纯收入及不良事件发生率。不良事件发生率数据来自2005年9月至2006年12月江苏、上海、广东、安徽、四川、重庆6省市IUD上市后的队列研究;经济数据来自上述地区2006年度国民经济和社会发展统计公报及统计年鉴。用直线相关与回归分析宫内节育器总不良事件、一般不良事件及严重不良事件发生率与人均收入的关系。结果上述6省市236个乡镇共计20?220例观察对象纳入统计分析。宫内节育器总不良事件发生率、一般不良事件发生率与人均收入呈正相关关系(分别为rs=0.336,P<0.05;rs=0.272,P<0.05);宫内节育器严重不良事件发生率与人均收入尚不能认为存在相关关系。结论经济水平较好的地区宫内节育器一般不良事件发生率较高,这可能与这些地区妇女的认知率高、自我健康保健意识强及耐受性低有关;但严重不良事件发生率与人均收入没有这种相关性,提示严重不良事件发生率很低,且多为客观指标,其报告更依赖相关卫生机构的处理能力、报告意识及管理水平。由于参与计生工作的人员均经过统一培训合格上岗,因而严重不良事件报告率无显著性差异,与所在地区经济水平关系不大。Objective To explore the relationship between macro-economic indicators and incidences of adverse events linked to intrauterine devices（IUDs）.Methods Data on IUD-associated adverse events were collected from a cohort study conducted between September 2005 and December 2006.Regional economic data were from the 2006 National Economic and Social Development Statistical Bulletins and Statistical Yearbooks of various regions.A total of 20,220 IUD users in 236 towns in Jiangsu,Shanghai,Guangdong,Anhui,Sichuan,and Chongqing provinces in China were included in this study.Linear correlation and regression analyses were used to analyze the relationships between regional income and total incidences of adverse events,incidences of mild adverse events,and incidences of severe adverse events.Results Incidences of total adverse events and mild adverse events were positively correlated with regional economic level（rs=0.336,P0.05;rs=0.272,P0.05）,while incidences of severe adverse events were not correlated with regional economic level.Conclusions The positive relationship between regional economic level and reported IUD-associated mild adverse events likely reflects income-related disparities in women seeking care and receiving treatment for mild adverse events.This points to a need to improve both public health education and the quality of health services,particularly in poorer areas.

关 键 词：宫内节育器 不良事件 经济水平 相关分析 

分 类 号：R169.4[医药卫生—公共卫生与预防医学]