刺五加根及根茎中紫丁香苷、刺五加苷E的提取工艺  

Optimization of Extraction Technology of Syringin and Glycosides E from Acanthopanax Stem and Root

作　　者：邵佳锋[1] 刘树民[1] 牟洪[1] 范振群[1] 安丽凤[1] 董杨[1] 

机构地区：[1]黑龙江中医药大学中医药研究院北药基础与应用研究省部共建教育部重点实验室,哈尔滨150040

出　　处：《中国实验方剂学杂志》2011年第4期5-7,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家"重大新药创制"科技重大专项"十一五"计划项目(2009ZX09103)

摘　　要：目的:优选刺五加的最佳提取工艺。方法:采用正交设计法,以HPLC测定提取物中紫丁香苷、刺五加苷E的含量。结果:最佳提取工艺为10倍量的80%乙醇回流提取3次,每次2h。结论:该提取工艺稳定,设计合理,重现性好,可为生产实践提供理论依据。Objective：To study the optimum extraction condition of Acanthopanax.Method：Orthogonal de-sign was used to study the extraction condition and the content of saponin was determined by HPLC.Result：The op-timized extract technology was as follows：crude drug of Acanthopanax was extracted with 10 times of 80% alcohol for 3 times,each time for 2 h.Conclusion：The optimized extraction was stable with good reproducibility,which could provide the basis for batch production.

关 键 词：刺五加 紫丁香苷 刺五加苷E 正交设计 提取工艺 

分 类 号：R283.6[医药卫生—中药学]