多指标综合评分法考察肠安Ⅰ号方醇提工艺  

Optimization of Ethanol Extraction Technology for Changan I with Multi-index Comprehensive Evaluation Method

作　　者：闫小平[1] 郭宇洁[1] 郑蕊[1] 杨俭勤[1] 唐旭东[1] 

机构地区：[1]中国中医科学院西苑医院,北京100091

出　　处：《中国实验方剂学杂志》2011年第4期12-15,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家科技部国际合作项目(2007DFA30560)

摘　　要：目的:多指标综合评分法考察肠安I号方醇提工艺。方法:采用正交试验设计,以黄芪甲苷和盐酸小檗碱的含量为评定指标,用多指标综合评分法进行数据处理,优化提取条件。结果:肠安I号方最佳醇提工艺为8倍量70%乙醇,分3次回流提取,每次2h。结论:该提取工艺合理,有效成分提取效率高。Objective：The ethanol extraction technology for Changan I was investigated with multi-index comprehensive evaluation method.Method：An orthogonal test was adopted in the study.The content of astragaloside Ⅳ and berberine hydrochloride was used as evaluation index.Data processing was carried out with multi-index com-prehensive evaluation method for optimizing the extraction condition.Result：The optimized extraction technology for Changan I was as follows：eight times volume of 70% alcohol,1 volume of the Chinese herbal medicines,3 succes-sive reflux extractions for 2 h of each.Conclusion：The optimized extraction technology was rational and the extrac-tion rate of the active components was high.

关 键 词：肠安I号方 黄芪甲苷 盐酸小檗碱 正交实验 综合评分法 

分 类 号：R283.6[医药卫生—中药学]