结缔组织疾病肾损害  

Kidney injury secondary to connective tissue disease

作　　者：王金泉[1] 季大玺[1] 

机构地区：[1]南京军区南京总医院全军肾脏病研究所,南京210002

出　　处：《中国实用内科杂志》2011年第2期97-99,共3页Chinese Journal of Practical Internal Medicine

摘　　要：结缔组织疾病常累及肾脏,其中继发于系统性红斑狼疮的狼疮性肾炎和继发于系统性小血管炎的血管炎性肾损害在临床上比较常见,且多数病情重、进展快,需要积极的诱导治疗和长期维持治疗。在这两方面,近年国内外研究均取得了明显的进展。文章介绍狼疮性肾炎和血管炎性肾损害的最新研究进展及南京军区南京总医院全军肾脏病研究所对这两类疾病治疗的体会。Summary：Connective tissue diseases often involve the kidney. Among the connective tissue disease, lupus nephritis and systemic small-vessel vasculitis-mediated renal lesions are the most often seen in clinic. The condi- tion of most patients with lupus nephritis and small-vessel vasculitis related renal lesions are serious and progress rapidly;they need intensive inducing immunosuppressive therapy and long-term maintenance therapy. Much pro- gress has been made in this field in recent years. The recent researches about lupus nephritis and small-vessel vas- culitis-related renal lesions are reviewed in this article. The experience on treatment of lupus nephritis and small- vessel vasculitis-related renal lesions in our institude is also introduced.

关 键 词：狼疮性肾炎 Wegner肉芽肿 微型多血管炎 多靶点治疗 

分 类 号：R5[医药卫生—内科学]