联合用药治疗婴幼儿轮状病毒性肠炎的疗效分析  

Effectiveness Analysis about Drug Combination on Infants with Rotavirus Enteritis

作　　者：何明生 

机构地区：[1]江西省修水县妇幼保健院,332400

出　　处：《中国现代药物应用》2011年第1期11-12,共2页Chinese Journal of Modern Drug Application

基　　金：江西省卫生厅中医药科研基金课题(课题编号:2008L0004)

摘　　要：目的探讨联合用药治疗婴幼儿轮状病毒性肠炎的疗效和安全性。方法将93名符合轮状病毒性肠炎诊断标准的患儿随机分成三组,对照组1给予黄芪2ml/(kg·次),2次/d,对照组2给予西米替丁10～15mg/(kg·次),1次/d,治疗组采用黄芪和西米替丁联合用药,疗程均为7d。结果治疗组抗原转阴时间、止泻时间、脱水纠正时间和住院天数较对照组明显缩短,差异有统计学意义(P<0.05);治疗组总有效率为90.3%,对照组1为64.5%,对照组2为51.6%,治疗组的有效率要明显高于两对照组(P<0.05),同时,治疗组的显效率也要高于两对照组(P<0.05);治疗组和对照组1均未见明显的不良反应。结论黄芪与西米替丁联合治疗婴幼儿轮状病毒性肠炎能有效缩短病程,提高疗效,且无明显不良反应,值得推广使用。Objective To explore the effectiveness and security about drug combination on infants with rotavirus enteritis.Methods 93 infants with rotavirus enteritis Were randomly divided into three groups,the control group 1 were given astragalus root 2 ml/（kg·time）and 2 times a day,the control group two were given cimetidine 10~15 mg/（kg·time） and one time a day,the treatment group were given drug combination of astragalus root and cimetidine,all the course were seven day.Results The time of antigens changing to feminine,antidiarrheal,correction of dehydration and the days in hospital were shortened in the treatment group compared with two control groups（P0.05）;The effective rate in treatment group was 90.3%,which was 64.5% in the control group 1 and 51.6% in the control group 2,the effective rate in treatment group was apparently higher than the two control groups（P0.05）,and the marked effective rate in treatment group was higher than the two control groups（P0.05）;there were no obvious adverse reaction in the treatment group and the control group 1.Conclusion The drug combination of astragalus root and cimetidine can shorten the care time,improve the care effectiveness and have no adverse reaction,which Worth promoting on the care of Infants with Rotavirus Enteritis.

关 键 词：黄芪 西米替丁 联合用药 婴幼儿轮状病毒性肠炎 

分 类 号：R725.1[医药卫生—儿科]