硫辛酸治疗2型糖尿病合并急性脑梗死的疗效观察  

作　　者：李兴明[1] 何小燕[1] 刘建祥[1] 

机构地区：[1]广东省粤北人民医院神经内科,韶关512026

出　　处：《中国医疗前沿》2011年第1期44-45,共2页China Healthcare Innovation

摘　　要：目的观察硫辛酸注射液治疗2型糖尿病合并急性脑梗死的临床疗效。方法随机将80例2型糖尿病合并急性脑梗死患者分为两组,在常规治疗基础上,治疗组(40例)用硫辛酸注射液0.6g加入0.9%NaCl液250ml静滴,1次/d,15d为1个疗程;对照组(40例)用胞二磷胆碱0.5g加入0.9%NaCl液250ml静滴,1次/d,15d为1个疗程。结果经过一个疗程治疗后,治疗组显效率75%明显高于对照组37.5%(P<0.05),治疗组NIHSS评分4.02±3.23明显低于对照组6.31±4.18(P<0.01)。结论硫辛酸注射液治疗2型糖尿病合并急性脑梗死有较好疗效,疗效优于胞二磷胆碱。Objective To observe clinical efficacy of the lipoic acid injection treatment of type 2 diabetic patients with acute cerebral infarction.Methods 80 patients of type 2 diabetic patients complicated with acute cerebral infarction were randomized into two groups： 40s in the trial group received treatment of injection lipoic acid 0.6g（which was added into 250ml 0.9%NaCl solution injection） by intravenous drip infusion once daily for 15 days,and 40s in the control group received injection citicoline 0.5g（which was added into 250ml 0.9%NaCl solution injection） also by intravenous drip infusion once daily for 15 days.Results After one course of treatment,there were significant differences in the curative rate（75% Vs 37.5%,P0.05） between treatment group and control group.The mean NIHSS score of in the treatment group（4.02±3.23） was significantly lower than the control group＇s（6.31±4.18）（P0.01）.Conclusion Lipoic acid injection is effective in treatting cerebral infarct of type 2 diabetic patients with acute cerebral infarction,and the efficiency of Lipoic acid was better than citicoline.

关 键 词：2型糖尿病 脑梗死 硫辛酸 

分 类 号：R587.1[医药卫生—内分泌]