改良法制备中性固体碘伏杀菌效果的测定  

EXAMINATION OF GERMICIDAL EFFICACY OF NEUTRAL SOLIDIODOPHOR PREPARED BY A MODIFIED METHOD

作　　者：沈建中[1] 钱万红[1] 张应阔[1] 姜志宽[1] 郑剑[1] 

机构地区：[1]南京军区军事医学研究所

出　　处：《中国消毒学杂志》1999年第2期74-78,共5页Chinese Journal of Disinfection

摘　　要：以研磨法制备中性固体碘伏。用其含１００ｍｇ／Ｌ有效碘溶液对金黄色葡萄球菌与大肠杆菌作用３ｍｉｎ，含２５０ｍｇ／Ｌ有效碘溶液对白色念珠菌作用８ｍｉｎ，含４０００ｍｇ／Ｌ有效碘溶液对枯草杆菌黑色变种芽胞作用１２０ｍｉｎ，杀灭率均达９９．９％。其杀菌作用随有效碘含量与作用时间增加而加强，随有机物增多而减弱。Solid iodophor was prepared by grinding dry iodine and polyvinylpyrrolidone at a ratio of 40210 to 55195 in a ceramic ball crusher. Then 1000 g of the solid iodophor was mixed with 100115 g of sodium bicarbonate and ground further for 1216 h at 40 to form deep brown-colored powder-like neutral solid iodophor containing about 16% available iodine, with pH value of its solution being 6772In suspension test, the killing rates of Staphylococcus aureus and Escherichia coli exposed to solution of the iodophor containing available iodine 100 mg/L for 3 min, Candida albicans exposed to solution of the iodophor containing available iodine 150 mg/L for 8 min and TBXBacillus subtilis var. niger spores exposed to solution of the iodophor containing available iodine 4000 mg/L were all 999%. The germicidal efficacy increased with increasing available iodine content and exposure time and decreased with increasing organic subtance contents. After stored in air-tight brown glass bottle at 1626 for 2 years, the iodophor powder lost 847% of its available iodine content.

关 键 词：中性碘伏 固体碘伏 杀菌作用 稳定性 消毒剂 

分 类 号：R979.7[医药卫生—药品]