膜荚黄芪中新异黄酮苷的结构鉴定  

A NEW ISOFLAVONE GLUCOSIDE FROM ASTRAGALUS MEMBRANACEUS

作　　者：曹正中[1] 曹园[1] 易以军[1] 吴永平[1] 冷宗康[1] 

机构地区：[1]江苏省药物研究所

出　　处：《药学学报》1999年第5期392-394,共3页Acta Pharmaceutica Sinica

摘　　要：黄芪为常用中药，有利尿、降压、强心、提高机体免疫功能等作用，临床应用广泛。为满足市场需要，江苏省从山东引种膜荚黄芪至徐州等地栽培，由于生态条件的差异，徐州黄芪外观呈一定木质化，有碍销售，为此，作者曾对其进行比较研究［１］，发现外观木质化与活性成分含量...AIM: To investigate the chemical constituents of the root of Astragalus membranaceus (Fisch) Bunge from Xu Zhou. METHODS: The compounds were separated by D101 macroporous absorbing resins and rechromatography on slilca gel. Their structures were determined by spectral analysis. RESULTS: Eight compounds were isolated. They were elucidated as 3methoxy5hydroxyisoflavone7ODglucoside ( 1 ) astramembrannin I ( 2 ), astramembrannin II (THZ 3 ), astragaloside III ( 4 TBZ), cyclocanthoside E ( 5 ), acetyastragalosid I ( 6 ), sitosterol ( 7 ) and daucosterol ( 8 ). CONCLUSION: Compound 1 was a new compound and 5 was isolated from the root of Astragalus membranaceus (Fisch.) Bunge for the first time.

关 键 词：膜荚黄芪 新异黄酮苷 结构 化学成分 

分 类 号：R284.1[医药卫生—中药学]