壳聚糖铜对断奶仔猪生产性能、肠道菌群及黏膜形态的影响  

Effects of Chitosan-Copper on Growth Performance and Intestinal Flora and Its Morphology in Weanling Piglets

作　　者：朱叶萌[1] 谢正军[1] 李云涛[1] 韩新燕[1] 

机构地区：[1]浙江大学饲料科学研究所/动物分子营养学教育部重点实验室,杭州310029

出　　处：《中国农业科学》2011年第2期387-394,共8页Scientia Agricultura Sinica

基　　金：浙江省科技计划项目(2008C22037)

摘　　要：【目的】研究壳聚糖铜对断奶仔猪生产性能、肠道菌群和肠道黏膜形态等方面的影响,为壳聚糖铜的利用提供科学依据。【方法】选择120头体重(7.8±0.2 kg)的"杜长大"三元杂交断奶仔猪随机分为4组。分别饲喂4种日粮:基础日粮组不添加外源铜(对照组),其它组在基础日粮基础上分别添加50、100 mg.kg-1壳聚糖铜(CS-Cu)、200 mg.kg-1硫酸铜,预饲期7 d,试验期30 d。【结果】50、100 mg.kg-1 CS-Cu和200 mg.kg-1硫酸铜组的日增重分别比对照组显著增加(P<0.05),料重比显著降低(P<0.05);添加CS-Cu可使盲肠和结肠内容物中大肠杆菌、沙门氏菌数量明显降低(P<0.05),而乳酸杆菌数量显著升高(P<0.05);与硫酸铜组相比,100 mg.kg-1 CS-Cu组空肠和回肠隐窝深度显著降低(P<0.05);空肠绒毛高度明显提高(P<0.05)。【结论】日粮中添加100 mg.kg-1CS-Cu与200 mg.kg-1硫酸铜,对提高断奶仔猪日增重和降低料重比具有等同的效果;日粮中添加CS-Cu具有改善肠道微生态平衡和肠道形态的作用。【Objective】The study was conducted to observe the effects of chitosan-copper（CS-Cu） on growth performance,intestinal flora and its morphology of piglets.【Method】 One hundred and twenty Duroc×Landraee×Yorkshire piglets（average BW of 7.8 ± 0.2 kg） were randomly divided into 4 treatment groups and fed with basic diet or basic diet supplemented with 50 mg·kg-1 CS-Cu,100 mg/kg CS-Cu and 200 mg·kg-1 CuSO4,respectively.The experiment lasted 30 days.【Result】 The average daily gain（ADG） of the CS-Cu groups and 200 mg·kg-1 CuSO4 group significantly increased（P〈0.05） and the feed gain ratio（F/G） significantly decreased（P〈0.05） comparing with the control group.The salmonella population and E.coli population in CS-Cu groups were lower than those of the control group（P〈0.05）,and lactobacillus population was higher than that of the control group（P〈0.05）.And the 100 mg·kg-1 CS-Cu group had an obvious increase in the jejunal villous height（P〈0.05） and a significant reduction in the intestine erypt depth（P〈0.05） compared with the 200 mg·kg-1 CuSO4 group.【Conclusion】 The results indicated that efficiency of 100 mg·kg-1 CS-Cu group was similar as 200 mg·kg-1 CuSO4 group,the addition of CS-Cu could modulate the micro-ecology balance and improve the intestinal morphology.And the diarrhea rate of the CS-Cu groups was obviously lower than that of the CuSO4 group.

关 键 词：壳聚糖铜 生产性能 肠道菌群 肠道形态 断奶仔猪 

分 类 号：S828[农业科学—畜牧学]