“一锅煮”合成新型含吡唑与苯并噻唑环的α-氨基膦酸酯衍生物  

One-pot Synthesis of Novel α-Aminophosphonate Derivatives Containing Pyrazole and Benzothiazole

作　　者：李建平[1] 仇记宽[1] 李会娟[1] 

机构地区：[1]河南师范大学化学与环境科学学院黄淮水环境与污染防治省部共建教育部重点实验室,河南新乡453007

出　　处：《合成化学》2011年第1期78-80,84,共4页Chinese Journal of Synthetic Chemistry

基　　金：河南省高校科技创新团队支持计划资助项目(2008IRTSTHN002)

摘　　要：在微波辅助、无溶剂、无催化剂条件下,以取代吡唑甲醛,2-氨基苯并噻唑和亚磷酸二乙酯为原料,"一锅煮"合成了6个新型含吡唑与苯并噻唑环的α-氨基膦酸酯衍生物,其结构经1H NMR,13C NMR和MS表征。A series of novel α-aminophosphonates derivatives containing pyrazole and benzothiazole were synthesized from substituted pyrazole aldehyde,2-aminobenzothiazole and diethylphosphone under microwave-assisted without catalyst and solvent.The structures were characterized by 1H NMR,13C NMR and MS.

关 键 词：Α-氨基膦酸酯 吡唑 苯并噻唑 微波无溶剂合成 

分 类 号：O626.2[理学—有机化学]