椎体成形术与降钙素治疗骨质疏松性椎体压缩骨折疗效对比  

Effective comparison between vertebroplasty and calcitonin in treating osteoporotic vertebral compression fractures

作　　者：严冬雪[1] 罗军[1] 

机构地区：[1]桂林医学院附属医院骨一科,广西桂林541001

出　　处：《现代医药卫生》2011年第4期485-487,共3页Journal of Modern Medicine & Health

摘　　要：目的:探讨椎体成形术及降钙素治疗骨质疏松性椎体压缩骨折(OVCFS)的临床疗效。方法:68例患者中,骨水泥成形术组46例,降钙素组22例。记录对比VAS及SF-12评分,骨水泥成形术组椎体高度化和Cobb角改善情况,降钙素组骨密度变化情况。结果:VAS评分及SF-12健康调查评分:降钙素组有波动,总体评分差于骨水泥成形术组。骨密度变化:降钙素组骨密度治疗后有提高。结论:骨水泥成形术治疗OVCFS能够迅速缓解疼痛,但降钙素止疼效果较骨水泥成形术滞后4周,长期应用止痛作用相对减弱,且其增加骨密度能力有限。To study the effects of vertebroplasty and drugs such as c alcitonin in treating osteoporotie vertebral compression fractures （OVCFs）.Methods：Among 68 cases of OVCFs,46 cases were treated with bone cementoplasty and 22 eases with calcitonin. A follow up was carried out to record and compare the visual analog scale （VAS）,SF-12 health survey scores,change of vertebral height, Cobb angle and bone mineral density （BMD） between the two groups.Results：VAS and SF-12 health survey scores in calcitonin group were fluctuated and lower than those in bone eementoplasty group.The bone mineral density was increased after treatment in calcitonin group.Conclusion：Bone ecmentoplasty can quickly relieve pain in treating OVCFs.The analgesic effect of calcitonin could be lagged for 4 weeks than bone cemcntoplasty and relatively weakened by long-term using. Calcitonin＇s ability to enhance BMD is limit.

关 键 词：骨质疏松性椎体压缩性骨折 骨水泥成形术 降钙素 

分 类 号：R6[医药卫生—外科学]