年龄对急性心肌梗死诱发老年高血压患者多器官功能衰竭的预测价值  

Prediction value of age for the prevalence of multiple organ dysfunction syndrome induced by acute myocardial infarction in old patients with hypertension

作　　者：崔华[1] 胡亦新[1] 叶平[1] 范利[1] 戴伟[2] 

机构地区：[1]解放军总医院南楼心血管二科,北京1008531 [2]解放军总医院信息管理科,北京1008531

出　　处：《军医进修学院学报》2011年第2期117-119,135,共4页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的探讨年龄对急性心肌梗死(AMI)诱发老年高血压患者多器官功能衰竭(MODSE)的预测价值。方法回顾性分1993年1月-2008年12月16年间因高血压在解放军总医院住院或住院期间出现高血压的60岁以上患者的病历资料19 996例,其中诊断AMI 2 966例,平均年龄(76.52±6.13)岁。调查各年龄段及各分界年龄上下老年高血压患者中因AMI并发MODSE的发生率,采用Spearman等级相关分析年龄与AMI诱发老年高血压患者MODSE发生率的相关关系,采用Pearsonχ2检验比较各分界年龄上下之间AMI诱发老年高血压患者MODSE发生率的差异后,再进一步采用Scheffe法比较六个不同年龄分界点每两个年龄分界点患者MODSE发生率的差异。结果年龄与AMI诱发老年高血压患者MODSE发生率呈正相关(r=0.341,P<0.001),AMI诱发老年高血压的MODSE发生率随年龄的增大而增高;75岁以上各分界年龄上下之间AMI诱发老年高血压患者并发MODSE的发生率差异最明显,具有统计学意义(P≤0.05)。结论75岁是影响AMI诱发老年高血压患者发生MODSE明显的分界年龄,75岁以上差异更加显著。因此年龄对AMI诱发老年高血压患者发生MODSE具有一定的早期预测价值,75岁以上老年高血压如合并AMI是MODSE的高危人群。Objective To study the prediction value of age for multiple organ dysfunction syndrome（MODS） induced by acute myocardial infarction（AMI） in old patients with hypertension.Methods Clinical data about 2 966 patients with hypertension at the age of over 60 years（mean 76.52±6.13 years） admitted to our hospital from January 1993 to December 2008 were retrospectively analyzed.The morbidity of MODS induced by AMI accompanying hypertension in old patients at different ages and different boundary ages were investigated.Spearman rank correlation was used to analyze the correlation between ages and incidence of MODS induced by AMI in old patients with hypertension.Pearson χ2 test was used to analyze the difference in morbidity of MODS induced by AMI in old patients with hypertension between above and below boundary ages.Scheffe χ2 test was used to compare the difference in morbidity of MODS between every two boundary ages.Results Age was positively correlated with the morbidity of MODS induced by AMI in old patients with hypertension（Spearman rank correlation coefficient=0.341,P0.001）.The morbidity of MODS induced by AMI in old patients with hypertension increased with increasing age.The morbidity of MODS induced by AMI was significantly different in old patients with hypertension between above and below 75 years or older（P0.05）.Conclusion The distinctly boundary age for the incidence of MODS induced by AMI in old patients with hypertension is 75.Age is valuable for early prediction of MODS induced by AMI in old patients with hypertension.

关 键 词：多器官功能衰竭 急性心肌梗死 老年人 高血压 年龄因素 

分 类 号：R541.4[医药卫生—心血管疾病]