胶束催化体系中的对映选择性环醚化反应(英文)  

Enantioselective Cycloetherification in a Micellar Catalysis System

作　　者：Bhupesh S. SAMANT Sunil S. BHAGWAT 

机构地区：[1]Natural Product and Medicinal Chemistry Research Group,Division of Pharmaceutical chemistry,Faculty of Pharmacy, Rhodes University Grahamstown [2]Department of Chemical Engineering,Institute of Chemical Technology

出　　处：《催化学报》2011年第2期231-234,共4页

基　　金：Supported by the Rhodes University Joint Research Committee (JRC,grant number 35047)

摘　　要：The enantioselective cycloetherification of substituted keto phenols into their corresponding dihydrobenzofuran derivatives was carried out using hydrogen peroxide and chiral quaternary ammonium iodide in micellar media. This approach increased the conversion rate of cycloetherification and also widened the scope of this particular reaction for various substituted keto phenols with electron withdrawing as well as electron donating functionalities. The use of a surfactant in the cycloetherification reaction increased the yield of the corresponding enantioselective dihydrobenzofuran four times. The conversion rate of keto phenols into their corresponding dihydrobenzofuran derivatives was proportional to the concentration of the surfactant used in the reaction.The enantioselective cycloetherification of substituted keto phenols into their corresponding dihydrobenzofuran derivatives was carried out using hydrogen peroxide and chiral quaternary ammonium iodide in micellar media. This approach increased the conversion rate of cycloetherification and also widened the scope of this particular reaction for various substituted keto phenols with electron withdrawing as well as electron donating functionalities. The use of a surfactant in the cycloetherification reaction increased the yield of the corresponding enantioselective dihydrobenzofuran four times. The conversion rate of keto phenols into their corresponding dihydrobenzofuran derivatives was proportional to the concentration of the surfactant used in the reaction.

关 键 词：enantioselective cycloetherification dihydrobenzofuran derivative micellar catalysis 

分 类 号：O643.32[理学—物理化学]