柴芩解热颗粒提取工艺研究  

Extraction process of Chaiqinjiere granules

作　　者：阎红梅[1] 张毅[2] 陈师农[2] 马玲[2] 

机构地区：[1]安徽中医学院药学院,安徽合肥230031 [2]安徽省药物研究所安徽省中药研究与开发重点实验室,安徽合肥230022

出　　处：《安徽医药》2011年第1期22-25,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的优选柴芩解热颗粒的最佳提取工艺。方法乙醇提取工艺以葛根素含量和浸膏得率为指标,水提取工艺以黄苓苷含量、浸膏得率为指标。采用正交试验优选柴芩解热颗粒最佳提取工艺。结果醇提最佳工艺条件为加8倍量70%乙醇,回流提取3次,每次1.5 h;水提最佳工艺条件为加10倍量水,煎煮3次,每次1.5 h。结论优选出的提取工艺稳定、合理、可行。Aim To study on the best extraction process of Chaiqinjiere granules.Methods The obtaining rate of extraction and the content of the puerarin was taken as indexes for the ethanol extraction process,and the obtaining rate of extract and the content of baicailin as indexes for the water extraction process.The extraction process of Chaiqinjiere granules was optimized by orthogonal design.Results The optimal conditions for the ethanol extraction of Chaiqinjiere granules was using 8 times of 70% ethanol solution,reflux 3 times,1.5 hours each time.The optimal process for the water extraction of Chaiqinjiere granules was in 10 times of water,decocting 3 times,1.5 hours for each time.Conclusion The extracting method is reasonable,stable,and suitable for industrialized production.

关 键 词：柴芩解热颗粒 提取工艺 正交实验 葛根素 黄芩苷 

分 类 号：TQ461[化学工程—制药化工]