力竭性游泳对大鼠胃组织丙二醛、游离巯基和ATP含量的影响  

THE STUDY ON THE RELATIONSHIP BETWEEN EXHAUSTIVE SWIMMING AND MDA、 FREE SH AND ATP CONTENTS IN RAT'S STOMACH TISSUES

作　　者：衣雪洁[1] 

机构地区：[1]沈阳体育学院生理教研室

出　　处：《中国应用生理学杂志》1999年第2期131-133,共3页Chinese Journal of Applied Physiology

摘　　要：目的：探讨力竭性游泳造成胃肠功能紊乱的机理。方法：３２只ＳＤ雄性大鼠随机分为４组，即对照组（Ｃ）；运动后即刻组（ＥＸ１）；运动后３０ｍｉｎ组（ＥＸ２）；运动后６０ｍｉｎ组（ＥＸ３），测定力竭性游泳后不同时相胃组织中ＭＤＡ，游离巯基和ＡＴＰ含量。结果：运动后即刻三项指标没有发生显著变化，但在运动３０ｍｉｎ和６０ｍｉｎ组中ＭＤＡ含量显著增加，而游离巯基和ＡＴＰ含量在这两个时相中显著下降，同时，解剖学观察也证实，力竭性游泳后３０ｍｉｎ和６０ｍｉｎ胃组织损伤严重。结论：运动源性自由基对胃组织有严重损伤，是造成运动性胃肠功能紊乱的重要因素。Aim: To study the mechanisms of gastrointestinal desorders inducud by exhaustive swimming. Methods: 32 male sprague dawley rats were divided into four goups (control group c; immediately after swimming group EX 1; thirty minutes after swimming group EX 2; sixty minutes after swimming group EX 3) to measure contents of MDA、Free SH and ATP in rat's stomach tissues. Results: MDA、Free SH and ATP contents had not significant changes immediately after exhaustive swimming. MDA contents increased significantly thirty, sixty minutes after swimming whitle Free SH and ATP contents decreased sifnificantly thirty, sixty minutes after swimming, at the same time, the anatomic observation also proved stomach tissues were severely damaged thirty, sixty minutes after exhaustive swimming. Conclusion: exercise induced free radical could lead to severe damage of stomach tissues, which was an important factor of exercise induced gastrointestinal disorders.

关 键 词：力竭性游泳 丙二醛 游离巯基 胃 ATP 

分 类 号：G804.21[文化科学—运动人体科学]