分散固相萃取法在突发性化学物中毒检测中的应用  

Application of Dispersive Solid Phase Extraction in Determination of Chemical Poisoning in Emergency

作　　者：徐炜[1] 姚志扬[1] 

机构地区：[1]江苏省连云港市疾病预防控制中心卫生监测科,222003

出　　处：《职业与健康》2011年第4期395-399,共5页Occupation and Health

基　　金：江苏省连云港市卫生局科研课题(EC330)

摘　　要：目的建立一种快速检测化学中毒毒物组分的新方法。方法以分散固相萃取法为前处理技术,乙酸乙酯为提取试剂,气相色谱-电子捕获检测器(GC-ECD)和气相色谱-氮磷检测器(GC-NPD)分析试样中10种毒物组分的残留。结果 10种毒物组分的加标回收率范围为72.8%～103.0%;相对标准差0.2%～8.3%;最低检出浓度0.10～0.50mg/kg。结论该方法可获得较高的回收率和精密度,较传统前处理方法更简便、快速,是一种更有效的前处理方法。[Objective] To establish a new method for rapid detection of toxic components of chemical poisoning.[Methods]Gas chromatography-electron capture detector （GC-ECD）and gas chromatography-nitrogen phosphorus detector （GC-NPD） were applied to analyze 10 toxic components of the residual with dispersive solid phase extraction as pretreatment technology and ethyl acetate as extraction agent.[Results]The recoveries ranged from 72.8%~103.0%;relative standard deviation was 0.2%~83%;minimum detectable limit was 0.10~0.50 mg/kg[Conclusion]This method can obtain high recovery and precision.It is a more effective pre-treatment method which is more simple,rapid than traditional pre-treatment methods

关 键 词：分散固相萃取 化学中毒 前处理 

分 类 号：R134[医药卫生—劳动卫生]