紫外-可见分光光度法测定盐酸法舒地尔注射液中盐酸法舒地尔的含量  

Fasudil Hydroehloride Content in Fasudil Hydroehloride Injection with Ultraviolet-Visible Spectrophotometry

作　　者：吕洁 孟祥军 邹春阳[2] 

机构地区：[1]辽宁卫生职业技术学院,辽宁沈阳110101 [2]沈阳医学院药物中心,辽宁沈阳110034

出　　处：《中国医药指南》2011年第5期26-28,共3页Guide of China Medicine

摘　　要：目的建立紫外-可见分光光度(UV-VIS)法测定盐酸法舒地尔含量的方法。方法采用对照品法,检测波长为275nm。结果制剂中辅料对主药测定无干扰,UV-VIS法测定盐酸法舒地尔的质量浓度在24～36μg/mL范围内线性关系良好(r2=0.9999)。平均回收率为99.3%,RSD为0.29%。结论本方法简便、准确、专属性强。能够满足控制本品质量的要求。Objective Ultraviolet-visible spectrophotometry（UV-VIS） was established to determine the fasudil hydroehloride content in the fasudil hydroehloride injection.Methods Reference standard method（λ-275nm） was used to determine the content of fasudil hydroehloride.Results The test of fasudil hydroehloride was 1inear within the range of 24～36μg/mL,r2=0.9999.The average recovery was 99.3%,RSD=0.29%.Conclusion The methods were simple and accurate,and the methods were suitable to determine the content.

关 键 词：紫外-可见分光光度法 盐酸法舒地尔注射液 含量测定 

分 类 号：R927.2[医药卫生—药学]