慢性肺心病急性加重期患者检测D-二聚体临床意义及与血气分析的相关性研究  

The clinical significance of the D-Dimer test in patients with acute serious chronic pulmonary heart disease and correlation analysis of D-Dimer and blood gas analysis

作　　者：朱敏锋[1] 

机构地区：[1]张家港市第一人民医院呼吸内科,江苏张家港215600

出　　处：《临床肺科杂志》2011年第3期354-355,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨慢性肺心病急性加重期患者检测D-二聚体临床意义及与血气分析的相关性研究。方法对60例住院治疗的慢性肺心病急性加重期患者及20例健康对照组分别检测D-二聚体、血气分析。结果 D-二聚体在慢性肺心病加重期患者升高,与对照组相比有显著性差异;D-二聚体与动脉血氧分压(PaO2)呈负相关。D-二聚体与动脉血二氧化碳分压(PaCO2)呈正相关。结论 D-二聚体有助于估计慢性肺心病纤溶状态,为早期预防血栓形成采取干预措施提供依据。临床应改善缺氧、通气及适当的抗凝治疗对控制病情有益。Objective To investigate the clinical significance of the D-Dimer test in patients with acute serious chronic pulmonary heart disease and correlation analysis of D-Dimer and blood gas analysis.Methods The D-Dimer and blood gas analysis were measured in 60 patients with acute serious chronic pulmonary heart disease and 20 normal subjects.Results The D-Dimer level was apparently higher in patients with acute serious chronic pulmonary heart disease and it has significant difference with control group.The D-Dimer is significantly negative correlation with arterial partial pressure of oxygen.And D-Dimer and arterial partial pressure of carbon dioxide appear positive correlation.Conclusion D-Dimer benefits the evaluation of the states of fibrinolysis,which provides basis for early preventive measures for thrombosis.The improvement of hypoxemia,ventilation and the anticoagulant therapy are beneficial to control chronic pulmonary heart disease patients′ condition.

关 键 词：慢性肺源性心脏病 D-二聚体 血气分析 

分 类 号：R541.5[医药卫生—心血管疾病]