Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides  

作　　者：ZHU JieMing,WANG Fei & HU JinBo CAS Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China 

出　　处：《Science China Chemistry》2011年第1期95-102,共8页中国科学（化学英文版）

基　　金：financially supported by the National Natural Science Foundation of China (20825209, 20832008, 20772144);the Chinese Academy of Sciences (Hundreds-Talent Program and Knowledge Innovation Program)

摘　　要：Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides has been successfully achieved.It was found that both the catalytic amount of sodium dithionite (Na2S2O4) and the stoichiometric amount of triethylborane (Et3B)/air can efficiently initiate the current free-radical atom transfer reaction.Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides has been successfully achieved.It was found that both the catalytic amount of sodium dithionite （Na2S2O4） and the stoichiometric amount of triethylborane （Et3B）/air can efficiently initiate the current free-radical atom transfer reaction.

关 键 词：radical fluoroalkylation SULFONAMIDE fluorine ALKENE ALKYNE 

分 类 号：O621.25[理学—有机化学]