3，3’，5，5’-四甲基联苯胺的合成研究  

Study on synthesis of 3,3',5,5'-tetramethylbenzidine

作　　者：黄斌[1] 阳军[1] 沈华平[1] 张征林[2] 

机构地区：[1]东南大学成贤学院化工与制药工程系,江苏南京210088 [2]东南大学化学化工学院,江苏南京210088

出　　处：《精细与专用化学品》2011年第2期17-19,共3页Fine and Specialty Chemicals

摘　　要：以2,6-二甲基苯胺为起始原料,经过成盐、溴化、水解及偶联反应合成了3,3’,5,5’-四甲基联苯胺,4步反应总收率46.56%。产品经^1HNMR表征。该方法具有操作简单、成本低等优点,适合工业化生产。3,3＇,5,5＇-Tetramethylbenzidine was synthesized by using 2,6-dimethyl aniline as the starting material via salting, bromination, hydrolysis and coupling. The total yield of four steps was 46. 56%. Structure of the product was confirmed by ~1HNMR. This method has many advantages, such as easy operation and low cost, which can be feasible to large scale preparation.

关 键 词：2 6-二甲基苯胺 成盐 溴化 水解 偶联 3 3’ 5 5’-四甲基联苯胺 

分 类 号：TQ246.31[化学工程—有机化工]