新疆伊犁地区人及家畜贝氏柯克斯体血清学调查  

Seroepidemiology of Q fever in Yili region of Xinjiang

作　　者：范德生 徐琪毅 禹惠兰[2] 彭勇 王誓闻[2] 张丽娟[2] 

机构地区：[1]伊犁州疾病预防控制中心,新疆伊宁835000 [2]中国疾病预防控制中心传染病预防控制所无形体研究室

出　　处：《疾病监测》2011年第1期15-17,共3页Disease Surveillance

基　　金：中美新发传染病合作项目(No.1U2GGH000018 -01);国家自然科学基金(No.30771854)~~

摘　　要：目的了解新疆伊犁地区人及家畜贝氏柯克斯体(Coxiella burnetii,Cb,俗称Q热立克次体)血清流行概况。方法采用WHO推荐的间接免疫荧光(IFA)方法检测人及家畜血清中的Q热病原体-贝氏柯克斯体特异IgG、IgM抗体。结果 24份门诊收集的不明发热患者血清中,4例为急性感染,2例为慢性感染或恢复期。85只动物调查结果显示,当地Q热感染主要为羊群,在检测山羊中,75.44%的动物IgMⅠ相抗体阳性,57.89%动物为IgGⅠ相抗体阳性。11.76%(10/85)动物有急性感染,2.35%(2/85)有慢性感染或在感染恢复期。结论新疆伊犁地区人及家畜普遍存在贝氏柯克斯体感染。有必要对该地区Q热进行更加深入的调查研究及采取必要的预防控制措施。Objective To understand the seroepidemiological characteristics of Q fever in Yili region in Xinjiang. MethodsImmunofluorescence assay （IFA） recommended by WHO was conducted to detect IgM and IgG to Coxiella burnetii,the pathogen of Q fever in human and livestock sera. Results By detecting 24 serum samples taken from the patients with unknown origin febrile illness,4 cases with acute Q fever and 2 chronic Q fever cases （or in convalescence phase） were detected. Up to 75.44% of goats were positive for Ⅰ phase antibody of IgM and 57.89% were positive for Ⅰ phase antibody of IgG. 11.76%（10/85） goats with acute infection of Coxiella burnetii and 2.35%（2/85） goats with chronic infection were identified. Conclusion Q fever was prevalent in human and animals in Yili region. It is necessary to conduct further and intensive epidemiological survey and take measures of prevention and control of Q fever in this region.

关 键 词：Q热 贝氏柯克斯体 血清学调查 新疆伊犁 

分 类 号：R376[医药卫生—病原生物学]