血清TGA、TMA、T_3、T_4、TSH鉴别甲亢型桥本甲状腺炎和Graves病  

Distinguishing hyperthyroidism type HT from GD by the values of TGA,TMA,T 3,T 4,TSH in serum

作　　者：姜义 姜瑛 关文曾 

出　　处：《白求恩医科大学学报》1999年第5期638-639,共2页Journal of Norman Bethune University of Medical Science

摘　　要：目的：鉴别甲亢型桥本甲状腺炎（ Ｈ Ｔ）和 Ｇｒａｖｅｓ 病（ Ｇ Ｄ），提高 Ｈ Ｔ 的诊断率，减少 Ｈ Ｔ 手术和不必要的抗甲状腺治疗。方法：以经甲状腺细针穿刺活检或术后病理证实为 Ｈ Ｔ 和 Ｇ Ｄ 的临床表现为甲状腺功能亢进的病人为研究对象，以活检前或术前清晨空腹血清 Ｔ Ｇ Ａ， Ｔ Ｍ Ａ， Ｔ３， Ｔ４ 和 Ｔ Ｓ Ｈ 为检测指标。结果：甲亢型 Ｈ Ｔ 和 Ｇ Ｄ 病人的 Ｔ Ｇ Ａ， Ｔ３ 有明显差异（ Ｐ＜ ００１）； Ｔ３／ Ｔ４， Ｔ Ｍ Ａ， Ｔ Ｓ Ｈ 有显著差异（ Ｐ＜ ０００１）； Ｔ４ 无差异（ Ｐ＞ ００５）。结论：血清 Ｔ３， Ｔ３／ Ｔ４ ， Ｔ Ｓ Ｈ， Ｔ Ｇ Ａ 和 Ｔ Ｍ Ａ 可以作为鉴别甲亢型 Ｈ Ｔ 和 Ｇ Ｄ 的重要检测指标。Objective:To distinguish hyperthroidism type HT from GD in order to enhance diagnosis rate of Ht and decrease unnecessary surgery or antithyroid therapy.Methods:The values of TGA,TMA,T 3,T 4 and TSH in serum of hyperthyroidism patients who have been proved HT or GD by thyroid biopsy or post surgery pathology were studied.Results:The values of T 3,T 3/T 4,TSH,TGA,and TMA were significantly different between in HT and in GD,but the values of T 4 were not different.Conclusion:The values of T 3,T 3/T 4,TSH,TGA and TMA in serum are useful indexes to distinguish hyperthyroidism type HT from GD.

关 键 词：甲状腺炎 GRAVES病 T3 T4 T3/T4 TSH TGA 

分 类 号：R581.4[医药卫生—内分泌] R581.1[医药卫生—内科学]