孕妇心脏安全性评估新指标的探索  

Exploration on new indicators for evaluating the cardiac safety of pregnant women

作　　者：有风芝[1] 赖厚君 詹直夫[3] 肖子夫[3] 肖守中[3] 杜德奇[1] 徐晓辉[1] 

机构地区：[1]郑州大学第三附属医院,河南郑州450052 [2]重庆市梁平县妇幼保健院 [3]重庆博精医学信息研究所

出　　处：《中国妇幼保健》2011年第3期358-359,共2页Maternal and Child Health Care of China

摘　　要：目的：探索孕产妇心脏安全性评估的新指标。方法：39名孕妇志愿纳入该研究。基于数字心音信号处理技术,测量、计算和分析孕妇的舒张期时限对收缩期时限的比值（D/S）,把D/S比值分为5级：Ⅰ级≥1.5;Ⅱ级：1.491.40;Ⅲ级：1.391.30;Ⅳ级：1.291.20;Ⅴ级：〈1.2。用该指标来评估舒张期心脏自身供血时间是否充足,并观察和记录在关注期间内出现的产科事件。结果：舒张期时限对收缩期时限的比值随孕周增加而变小;〈32孕周组的D/S为1.39±0.40,3239孕周组的D/S为1.25±0.44,各组间D/S值比较无统计学差异（P〉0.05）。D/S比值≥1.5者9例,而D/S比值〈1.5者30例。这是一个不利于孕妇心脏健康的变化。其中有1例D/S非常低（0.59）的孕妇,D/S比值在Ⅴ级,在剖宫产手术准备中死亡。结论：在孕妇保健工作中应该对D/S比值给予充分的重视,应当关注孕期D/S比值降低程度与孕妇和胎儿预后的关系以及产后D/S恢复至≥1.5的速度和程度。该项研究所用的方法客观、简单、费用低、快速并且安全。Objective：To explore new indicators for evaluating the cardiac safety of pregnant women.Methods：39 pregnant women participated in the study voluntarily;based on the digital technique of heart sound signal processing,the ratio of diastolic to systolic duration（D/S） during pregnancy was measured,calculated and analyzed.The D/S values were divided into five grades： grade Ⅰ： ≥1.5;gradeⅡ： 1.491.40;grade Ⅲ： 1.391.30;grade Ⅳ： 1.291.20;grade Ⅴ： 〈1.2.The indicator was used to evaluate if the perfusion time of the heart itself during diastolic phase was sufficient.The obstetric events during the period were observed and recorded.Results：D/S value decreased with gestational weeks;the D/S value of pregnant women less than 32 gestational weeks was（1.39±0.40）,the D/S value of pregnant women of 3239 gestational weeks was（1.25±0.44）,there was no significant difference in D/S value among different groups（P〉0.05）.The amounts of pregnant women whose D/S value≥1.5 and 〈1.5 were 9 and 30,respectively,and the change was not good for cardiac health of pregnant women;one pregnant woman with very low D/S value（0.59,grade Ⅴ） died during preparation period for caesarean section.Conclusion：D/S value should be paid attention to sufficiently in health care work for pregnant women.The relationship between degree of D/S value decrease during pregnancy and prognosis of pregnant women and fetuses,and the speed and extent of D/S value returning to≥1.5 after delivery should be concerned.The method used in the study is objective,easy,inexpensive,rapid and safe.

关 键 词：孕产妇 心脏 安全性评估 

分 类 号：R715.3[医药卫生—妇产科学]