46,XY性发育疾病的研究进展  

Progress in researches on 46,XY disorders of sexual development

作　　者：段守兴[1] 李建宏[1] 蒋学武[1] 

机构地区：[1]汕头大学医学院第二附属医院小儿外科,广东汕头515041

出　　处：《中华男科学杂志》2011年第2期156-159,共4页National Journal of Andrology

基　　金：国家自然科学基金(305719035);广东省自然科学基金(815150310200029)~~

摘　　要：46,XY性发育疾病是临床上一类复杂问题,不仅涉及医疗,也关系着社会、伦理等诸多方面,是一个需要长期甚至终生进行身心随访和诊治的疾病。如能早期诊断、合理治疗,不但可使患者第二性征适当发育,而且可有效防止性腺恶变的可能。近年来由于环境污染等因素的影响,46,XY性发育疾病的发生率在全球范围呈上升趋势,临床应加深对其的认识并提高警惕,及早诊治,最大程度地改善患者预后。本文结合其病因、新分类及诊疗方面的研究现状作一综述。46,XY disorders of sexual development （46,XY DSD） are a group of complicated clinical conditions,which involve medical care,society,ethics and many other aspects.As chronic diseases,they necessitate long-term or even lifelong physical and mental follow-up and treatment.Early diagnosis and reasonable treatment could not only achieve appropriate development of the secondary sexual characteristics,but also effectively prevent gonadal malignancy.In recent years,environment pollution and other factors are contributing to the increasing incidence of 46,XY DSD all over the world.A deeper clinical insight into these disorders helps their earlier diagnosis and maximum improvement of prognosis.The etiology,new classification and treatment of 46,XY DSD are reviewed in this article.

关 键 词：46 XY性发育疾病 病因 分类 诊疗 

分 类 号：R726.5[医药卫生—儿科]