间歇性高容量血液滤过救治ICU病房多器官功能障碍综合征疗效分析  

Effect of pulse high volume hemofiltration for treatment of multiple organ dysfunction syndrome

作　　者：李莉[1,2] 史伟[3] 刘易林[2] 李颖[2] 杨翠华[2] 饶明清[2] 马莲英[2] 邓道喜[2] 

机构地区：[1]南方医科大学研究生学院,广东广州510515 [2]粤北人民医院重症医学科,广东韶关512026 [3]广东省人民医院肾内科,广东广州510080

出　　处：《南方医科大学学报》2011年第2期344-346,共3页Journal of Southern Medical University

基　　金：韶关市医药卫生科研计划项目(Y10024)

摘　　要：目的探讨间歇性高容量血液滤过(PHVHF)对多器官功能障碍综合征(MODS)治疗效果。方法 PHVHF治疗MODS患者25例。结果 25例患者治疗中血流动力学稳定,血尿素氮、肌酐及血钾下降(P<0.01),氧合指数好转(P<0.05)。急性生理学及慢性健康况评分Ⅱ(APACHE-Ⅱ评分)降低(P<0.05)。18例痊愈出院,5例死亡,2例自动出院,治愈好转率72%,死亡率20%。结论 PHVHF可明显改善MODS预后,患者耐受性好。Objective To evaluate the effects of pulse high volume hemofiltration（PHVHF） in the treatment of multiple organ dysfunction syndrome（MODS）.Methods？Twenty-five patients with MODS received treatment with PHVHF.Results The 25 patients showed significantly decreased BUN,Scr,and K＋ levels after the treatment（P0.01）,and PaO2/FiO2 was improved in almost all the patients（P0.05）.The APACHEII scores were significantly improved（P0.05） in these patients and 18 of them were cured and discharged.PHVHF therapy was associated with a survival rate of 72%.Conclusion PHVHF can be effective for treatment of MODS.

关 键 词：间歇性高容量血液滤过 多器官功能障碍综合征 ICU 

分 类 号：R459.5[医药卫生—治疗学] R459.7[医药卫生—临床医学]