Tei指数评价缺氧新生儿左心室功能障碍的作用研究  

Evaluation of left ventricular dysfunction by Tei index in neonates with hypoxemia

作　　者：王乐[1] 周英[1] 李明霞[1] 

机构地区：[1]新疆医科大学第一附属医院新生儿科,新疆乌鲁木齐830054

出　　处：《中国当代儿科杂志》2011年第2期111-114,共4页Chinese Journal of Contemporary Pediatrics

摘　　要：目的探讨Tei指数在评价缺氧新生儿左心室功能障碍中的作用。方法 52例低氧血症新生儿(轻度20例,中重度各16例)和40例正常新生儿作为研究对象,于生后1、3、7 d用多普勒超声心动图测定反映心脏收缩及舒张功能的指标:左心室射血分数(LVEF)、二尖瓣口E/A值;左心室Tei指数(LV-Tei)。结果 (1)中度低氧血症组生后1、3 d LVEF、左室E/A值明显低于对照组(P<0.01);重度低氧血症组生后1、3、7 d LVEF、左室E/A值均明显低于对照组(P<0.01或0.05)。(2)轻度低氧血症组生后1 d、中度及重度低氧血症组生后1 d、3 dLV-Tei值明显高于对照组(P<0.01)。(3)低氧血症组生后1 d、3 d PaO2与LV-Tei呈负相关(r=-0.50,P<0.05;r=-0.71,P<0.01)。结论 LV-Tei可敏感地发现低氧血症患儿左心室功能下降,对临床的诊治有重要的指导作用。Objective To study the role of Tei index in the evaluation of left ventricular dysfunction in neonates with hypoxemia.Methods Fifty-two neonates with hypoxemia（20 mild,16 moderate,16 severe） and 40 normal neonates（control group） were enrolled.On postnatal days 1,3 and 7,Doppler echocardiography was used to measure the indexes reflecting systolic and diastolic cardiac functions： ejection fraction of left ventricular（LVEF）,E/A ratio of mitral value and Tei index of left ventricular（LV-Tei）.Results LVEF and E/A ratio of left ventricular in the moderate hypoxemia group were significantly lower than those in the control group on postnatal days 1 and 3（P0.01）.LVEF and E/A ratio of left ventricular in the severe hypoxemia group were significantly lower than those in the control group on postnatal days 1,3 and 7（P0.01 or 0.05）.Compared with the control group,LV-Tei increased significantly in the mild hypoxemia group on postnatal day 1 and increased significantly in the moderate and severe hypoxemia groups on postnatal days 1 and 3（P0.01）.There was a negative correlation between PaO2 and LV-Tei in the hypoxemia group on postnatal days 1 and 3（r=-0.50,P0.05;r=-0.71,P0.01 respectively）.Conclusions LV-Tei can be used as a sensitive indicator for the evaluation of left ventricular dysfunction in neonates with hypoxemia.

关 键 词：多普勒超声心动图 TEI指数 低氧血症 新生儿 

分 类 号：R722.1[医药卫生—儿科]