齿叶白鹃梅叶中黄酮类成分的分离与结构鉴定  

Chemical constituents of the leaves of Exochorda serratifolia S.Moore

作　　者：才谦[1] 王聪[1] 刘玉强[1] 

机构地区：[1]辽宁中医药大学药学院,辽宁大连116600

出　　处：《沈阳药科大学学报》2011年第3期190-191,231,共3页Journal of Shenyang Pharmaceutical University

摘　　要：目的研究齿叶白鹃梅叶的化学成分。方法采用硅胶柱色谱、重结晶和Sephadex LH-20凝胶柱色谱的方法进行化学成分的分离和纯化,根据化合物的理化性质和波谱数据鉴定其结构。结果分离得到6个黄酮类化合物,经鉴定为芹菜素(apigenin1,),木犀草素(luteolin,2),槲皮素(querce-tin,3),槲皮素-3-O-β-D-葡萄糖苷(quercetin-3-O-β-D-glucopyranoside,4),芹菜素-7-O-β-D-葡萄糖苷(apigenin-7-O-β-D-glucopyranoside,5),芹菜素-7-O-β-D-新橙皮糖苷(apigenin-7-O-β-D-neosphero-side,6)。结论化合物1-6均首次从此植物中分离得到。Objective To study the chemical constituents of the leaves of Exochorda serratifolia S. Moore. Methods Isolation and purification were carded out on the chromatography of silica gel and Sephadex LH-20. Their structures were elucidated on basis of physicochemical properties and spectral data. Results Six compounds were isolated and identified as apigenin （ 1 ）, luteolin （ 2 ）, quercetin （ 3 ）, quercetin-3-O-β-D-glucopyranoside （ 4 ） , apigenin-7-O-β-D-glucopyranoside （ 5 ） and apigenin-7-O-β-D-neospheroside （ 6 ）. Conclusions Compounds 1-6 are isolated from this plant for the first time.

关 键 词：齿叶白鹃梅 化学成分 黄酮类 

分 类 号：R94[医药卫生—药剂学]