完全综合指标法评价我院围术期预防用药干预措施的效果  

Effect Evaluation of Intervention Measures for Perioperative Prophylactic Drug Use in Our Hospital by Fully Comprehensive Index Method

作　　者：茹爱忠[1] 李柱[2] 程文君[1] 刘金花[3] 杜柏荣[1] 倪建峰[1] 许衍峰[1] 

机构地区：[1]甘肃酒泉市人民医院药剂科,酒泉市735000 [2]甘肃酒泉市人民医院泌尿外科,酒泉市735000 [3]甘肃酒泉市人民医院检验科,酒泉市735000

出　　处：《中国药房》2011年第10期884-887,共4页China Pharmacy

摘　　要：目的:评价我院实施双干预法(行政干预和技术干预)对围术期抗菌药物不合理应用的效果。方法:将我院2008年5-11月的58份出院患者病历设为非干预组,2009年5-11月的52份在院患者病历设为干预组,采用完全综合指标法对2组抗菌药物应用方面的数据进行对比分析。结果:与非干预组相比,干预组平均药费、平均抗菌药物费用均有所降低,尤其是平均抗菌药物费用降低明显(P<0.05),从972.00元降至657.53元,其中以乳腺手术和阑尾摘除术费用降低最为明显;经干预后,Ⅰ类切口手术术前用药比例从0%上升至11.11%,术前+术后用药比例从10.00%上升至44.45%;预防用药合理性比例2组有极显著性差异,经干预后,基本合理比例从3.45%上升至32.69%,不合理比例从79.31%下降至34.62%。结论:通过实施双干预措施,可为医院进一步规范抗菌药物应用、降低单病种费用提供一种有效且可行的模式。OBJECTIVE： To evaluate the effect of dual interventions （administrative intervention and technical intervention） on irrational use of antimicrobial agents in perioperative period in our hospital. METHODS： 58 medical records of discharged patients in our hospital from May to Nov. 2008 were used as non-intervention group, and 52 medical records of discharged patients from May to Nov. 2009 were intervention group. Application of antimicrobial agents of two groups was analyzed comparatively by fully comprehensive index method. RESULTS： Compared with non-intervention group, average drug cost and average antimicrobial agents cost of intervention group decreased to some extent, especially average antimicrobial agents cost decreased from 972.00 yu- an to 657.53 yuan （P〈0.05）. The cost of mammary gland operation and appendectomy decreased obviously. The proportion of drug use before type I incision operation increased from 0 % to 11.11%. The proportion of drug use before and after operation in- creased from 10.00% to 44.45%. The proportion of reasonable prophylactic drug use had a very significant difference between two groups. The proportion of reasonable drug use increased from 3.45% to 32.69% while that of unreasonable drug use decreased from 79.31% to 34.62 %. CONCLUSION： Double intervention measures are effective and feasible model for further standardizing application of antimicrobial agents and reducing the cost of single disease.

关 键 词：完全综合指标法 双干预措施 预防用药 影响 

分 类 号：R969.3[医药卫生—药理学] R287[医药卫生—药学]