变应性鼻炎Th1/Th2细胞失衡及其相关细胞因子与IgE水平的相关性研究  

Relevant Research of Th1/Th2 Cells' Unbalanced,Related Cell Factor and IgE Level in Allergic Rhinitis

作　　者：聂玲娟[1] 王东方[2] 

机构地区：[1]南京中医药大学,江苏南京210029 [2]南京中医药大学附属医院,江苏南京210029

出　　处：《辽宁中医药大学学报》2011年第3期86-88,共3页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：变应性鼻炎(AR)是IgE介导的,由多种免疫活性细胞和细胞因子参与的鼻黏膜慢性炎症反应性疾病,其发病的重要免疫学基础是Th1与Th2细胞之间的失衡,主要表现为Th2细胞优势。文章就AR的Th1与Th2失衡机理,相关细胞因子与血清IgE水平的相关性,中药治疗AR前后血清IgE、相关细胞因子的变化,探讨药物治疗的免疫学机理。Allergic rhinitis（AR）is IgE mediated,participated in the nose mucous membrane chronic inflammation reactivity disease by a variety of immune cells and the correlation cell factor.Its morbidity important immunology foundation is the imbalance of Th1/Th2 cells,the main performance is the Th2 cell superiority.In this paper,we discussed on the mechanism of the imbalance of Th1/Th2 cells and the relevance of the cell factor and blood serum IgE level.Meanwhile,we want to know the changes of the cell factor and blood serum IgE level after traditional Chinese medicine treatment of AR and to explore the immunological mechanism of drug therapy.

关 键 词：变应性鼻炎 Th1与Th2失衡 细胞因子 IGE 中药 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]