检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
机构地区:[1]南京中医药大学 [2]南京海陵中药制药工艺技术国家工程研究中心,江苏南京210049
出 处:《安徽医药》2011年第2期158-160,共3页Anhui Medical and Pharmaceutical Journal
基 金:南京市2010年第二批科技发展计划项目(No201002018)
摘 要:目的研究并建立南五味子软胶囊的含量测定方法。方法采用高效液相-紫外检测法,以四氢呋喃-甲醇-水(10∶30∶60)为流动相,检测波长为280 nm,测定五味子酯甲和五味子甲素的含量。结果五味子酯甲在0.72~7.2μg范围内呈良好的线性关系,五味子甲素在0.56~5.6μg范围内呈良好的线性关系;加样回收率五味子酯甲为100.13%,RSD为1.05%,五味子甲素为99.53%,RSD为0.81%;精密度良好,五味子酯甲和五味子甲素的RSD分别为1.20%、1.02%;重复性也很好,五味子酯甲和五味子甲素的RSD分别为0.95%、1.06%。结论本方法稳定可靠,灵敏简便,重现性好,可作为南五味子软胶囊的的质量控制方法。Aim To develop an HPLC-UV method for determination of Fructus schisandrae sphenantherae softcapsule.Methods UV-detector was used to detect schisantherin A and schiandrin A,and the proportion of mobile phase was methanol∶ tetrahydrofuran∶ pure water(30∶ 10∶ 60),The wavelength was 280 nm.Results The calibration curve was good and the linear range of schisantherin A concentration was from 0.72 μg to 7.2 μg.The linear range of schiandrin A concentration was from 0.56 μg to 5.6 μg.The average recovery of schisantherin A was 100.13% with RSD equal to 1.05%,and the other was 99.53% with RSD equal to 0.81%.Precision and repeatability were good with RSD equal to 1.20%,1.02%and the other RSD equal to 0.95%,1.06%.Conclusion The method is simple,convenient,accurate with a good reproducibility.It can be applied to the quality control of Fructus schisandrae sphenantherae softcapsule.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.229