CRP、WBC计数与冠心病病情的相关分析  

Clinical Study of Correlation between C-reactive Protein,Peripheral White Blood Cell Count,Neutrophil and the Severity of Coronary Heart Disease

作　　者：朱德才[1] 祁彬[1] 杨光耀[1] 许海侠[2] 

机构地区：[1]安徽省亳州市人民医院南院急诊科,236800 [2]江苏省苏州大学第一附属医院心内科,215006

出　　处：《中华全科医学》2011年第3期369-370,共2页Chinese Journal of General Practice

摘　　要：目的探讨C反应蛋白(CRP)、外周血白细胞计数(WBC)及中性粒细胞计数(NEU)对冠心病严重程度的关系。方法选择急性冠脉综合症(AMI)53例(A组)、不稳定性心绞痛(UA)58例(B组)、稳定型心绞痛(SA)72例(C组)及非冠心病对照者52例(D组),分别检测、比较各组间CRP、WBC及NEU水平差异。结果急性心肌梗死组(AMI)组的CRP、WBC及NEU水平均显著高于不稳定性心绞痛组(UA)、SA组及对照组(P<0.01),AMI、UA组的3项指标水平亦显著高于对照组(P<0.05)。结论冠心病患者血清CRP及外周血WBC比健康人高,根据患者血清CRP及外周血WBC可评估临床冠心病患者病情严重程度,对疾病的危险分层和预后判断具有重要的临床价值。Objective To investigate the relationship between C-reactive protein （CRP）, peripheral white blood cell count （WBC） ,neutrophil count（NEU） and the severity of coronary heart disease（CHD）. Methods CRP, WBC and NEU were determined in 53 cases of patients with acute myocardial infarction（AMI） （ group A） ,58 cases with unstable angina（UA） （ group B） , 72 cases with stable angina（SA） （group C ）and 52 healthy controls （group D）. The three groups were compared CRP, WBC, NEU levels with each other. Results CRP, WBC and NEU in AMI group were all significant higher than those of UA group, SA group and control group（P 〈0.01 ）. Moreover,the three indexes in group A, group B were also significantly higher than control group （ P 〈 0.05）. Conclusion Serum CRP and peripheral WBC of patients with coronary heart diseases were higher than those of healthy people. So according to serum CRP and peripheral WBC can assess the severity of clinical coronary heart disease patients, in addition,serum CRP and peripheral WBC had important value in the disease risk stratification and prognosis.

关 键 词：C反应蛋白 外周血白细胞 中性粒细胞 冠心病 相关性 严重程度 

分 类 号：R541.4[医药卫生—心血管疾病]