多囊卵巢综合征子宫内膜容受性的影响因素  

Contributing Factors of Endometrial Receptivity in Polycystic Ovary Syndrome

作　　者：许榕倩[1] 刘芸[2] 

机构地区：[1]福建中医药大学,福州350108 [2]解放军南京军区福州总医院妇产科,福州350025

出　　处：《医学综述》2011年第3期426-428,共3页Medical Recapitulate

摘　　要：多囊卵巢综合征(PCOS)是引起月经失调和不孕的常见内分泌障碍性疾病。PCOS不孕的主要原因有不排卵和卵母细胞质量差等。但经药物纠正排卵后,仍存在低妊娠率、高流产率的现象。其原因之一是PCOS患者内分泌及代谢的改变使其子宫内膜容受性降低。现从形态学、分子生物学和基因学角度探讨PCOS子宫内膜容受性降低的影响因素。Polycystic ovary syndrome（PCOS）is a common endocrine disorder that causes menstrual dysregulation and infertility.PCOS-associated infertility results mainly from anovulation and compromised oocytes.The medical treatment improves the ovulation,showing a low pregnancy rate and high abortion rate though.One of the caused underlying this problem is the reduced endometrial receptivity caused by the disruption of endocrine function and metabolism in PCOS patients.The article mainly reviews the contributing factors of reduction in endometrial receptivity in PCOS in the sense of morphology,molecular biology,and genetics.

关 键 词：多囊卵巢综合征 子宫内膜容受性 胞饮突 整合素 

分 类 号：R711[医药卫生—妇产科学]