合胞病毒肺炎T细胞趋化值和总IgE的变化  

The Changes of the Chemotaxis of T Cell and Total IgE in Patients with RSV Pneumonia

作　　者：陆斌杰[1] 曹兰芳[1] 于清[1] 金燕梁[1] 许以平[2] 朱丽君[2] 

机构地区：[1]上海第二医科大学附属仁济医院儿科,200001 [2]上海第二医科大学附属仁济医院老慢支研究室

出　　处：《上海第二医科大学学报》1999年第5期426-427,434,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：目的探讨T淋巴细胞趋化功能及IgE的产生与呼吸道合胞病毒（RSV）肺炎的发病关系，寻找检测细胞免疫功能的新方法。方法采用微量玻片法和放射免疫法，观察RSV肺炎患儿外周血T淋巴细胞趋化值及总IgE的变化。结导RSV肺炎患儿外周血T淋巴细胞趋化值为4.96％±0.29％，总IgE为（567.00±169.60）mg／L，明显高于正常对照组（P＜0.01）。给论RSV肺炎的患儿类同于支气管哮喘患儿，存在明显的免疫功能紊乱，表现为T淋巴细胞起化性和B淋巴细胞分泌IgE明显的增高。Objective To explore the relationship between the chemotaxis of T- cell,the procreation of IgE and the incidence of RSV pneumonia, and also to find a new way to study the function of cell immunity. Methods Using trace sheet glass and radioisotopic immunology, detecting the chemotactic numerical value of T-cell and the changes of IgE in the patients' peripheral blood, and compare with children who were controlled.Results The chemotactic numerical value of T- cell of 28 cases of RSV pneumonia is 4.96% ±0.29% and their IgE is (567.00±169.60)mg/L, both much higher than 34 cases of controll group (P<0.01). Conclusion There is obvious disturbance of immune function in children with RSV pneumonia just like bronchial asthma, This study show that the rising of chemotactic numerical value of T - cell and IgE can be a new way to explore the function of cell immunity.

关 键 词：肺炎 IGE 合胞病毒肺炎 T细胞趋化值 

分 类 号：R563.103[医药卫生—呼吸系统]