手性环状二胺催化的不对称Diels-Alder反应  

Application of the Novel Chiral Diamines in Diels-Alder Reaction

作　　者：朱其明[1,2] 黄汉民[1] 夏春谷[1] 

机构地区：[1]中国科学院兰州化学物理研究所,羰基合成与选择氧化国家重点实验室,甘肃兰州730000 [2]中国科学院研究生院,北京100039

出　　处：《分子催化》2011年第1期6-10,共5页Journal of Molecular Catalysis(China)

摘　　要：研究了一种结构新颖、合成路线简单的手性二胺催化的Diels-Alder反应,考察了各种Brφnsted酸助催化剂、温度、溶剂和手性二胺分子中不同的取代基对反应的影响.研究结果表明:该类催化剂在催化Diels-Alder反应中表现出较高的催化活性和中等的立体选择性.A series of chiral diamines with novel rigid structure have been successfully applied in the Diels-Alder reaction.The effect of reaction conditions such as Brnsted acid,temperature,solvent and different substitutes on the diamines was also extensively investigated.The results showed that the Diels-Alder reaction processed smoothly with high yield and moderate enantiomeric excess under the optimized reaction conditions.

关 键 词：手性二胺 BRΦNSTED酸 DIELS-ALDER反应 不对称催化 

分 类 号：O643.3[理学—物理化学]