脑电双频指数监测对丙泊酚全麻患者术中做梦发生率的影响  

Effect of bispectral index monitoring on the incidence of intra-operative dreaming during propofol-based anaesthesia

作　　者：吴长毅[1] 张梁[1] 邓莹[1] 李岩[1] 张利萍[1] 郭向阳[1] 

机构地区：[1]北京大学第三医院麻醉科,北京100191

出　　处：《中国临床药理学杂志》2011年第2期92-95,共4页The Chinese Journal of Clinical Pharmacology

摘　　要：目的观察脑电双频指数(BIS)监测对丙泊酚(静脉麻醉药)全麻患者术中做梦发生率的影响。方法选择200例择期丙泊酚全麻手术患者,随机均分为BIS监测组和对照组。BIS监测组于术中根据BIS值来调控麻醉深度;而对照组监测BIS需麻醉者根据自身经验和手术需要来调控麻醉深度。分别于术后第1天和第4天随访患者术中做梦及术中知晓的发生率。结果 BIS监测组于术后第1天和术后第4天随访均无患者发生术中做梦;而对照组术后第1天和术后第4天随访术中做梦的发生率分别为6.3%和5.2%,显著高于BIS监测组(P<0.05)。BIS监测组于术后随访有1例患者发生术中知晓;而对照组无患者发生术中知晓。结论 BIS监测可显著降低丙泊酚全麻患者术中做梦的发生率。Objective To observe the effect of bispectral index（BIS） monitoring on the incidence of intra-operative dreaming during propofol-based anaesthesia.Methods In this study,200 adult surgical patients were randomly assigned to receive BIS-guided anaesthesia or a standard practice group in which BIS was recorded but did not guide drug administration.The patients were interviewed about dreaming and awareness two times at 1 day and 4 days after surgery.Results In the control group,intra-operative dreaming was reported by 6.3% and 5.2% of patients at 1 day and 4 days after surgery,respectively.None of the patients in the BIS-guided group reported the occurrence of dreams at the two time points.The incidence of dreaming during operation in the control group was significantly higher than those in the BIS-guided group（P〈0.05）.There was one report of awareness in the BIS-guided group and no report in the control group.Conclusion BIS monitoring reduces the incidence of intraoperative dreaming during propofo-based anaesthesia.

关 键 词：脑电双频指数 做梦 丙泊酚 静脉麻醉 

分 类 号：R972.1[医药卫生—药品] R614.24[医药卫生—药学]