835例慢性湿疹患者斑贴试验分析及临床意义  

The analysis and the clinical significance of patch test on 835 cases of chronic eczema patients

作　　者：吴蓓玲[1] 孙洁[1] 余土根[1] 魏盛[2] 韩德鑫[2] 陈霞[2] 程立峰[2] 贾丽莹[2] 

机构地区：[1]浙江省中医院皮肤科,杭州310006 [2]浙江中医药大学,杭州310053

出　　处：《中国卫生检验杂志》2011年第1期103-105,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:研究慢性湿疹患者斑贴试验的结果及临床意义。方法:对本科门诊确诊的835例慢性湿疹患者进行斑贴试验,并对结果作统计学处理。结果:斑贴试验总阳性率85.39%,性别、年龄差别无统计学意义,局限型皮损者阳性率看似高于泛发型,但无统计学意义。阳性率居前5位的变应原依次为:重铬酸钾、硫酸镍、卡巴混合物、甲醛和芳香混合物,其中卡巴混合物的阳性率男性明显高于女性,芳香混合物阳性率女性明显高于男性。41.55%的病例同时存在3种及以上的阳性变应原。结论:重铬酸钾、硫酸镍、卡巴混合物、甲醛和芳香混合物是本地区慢性湿疹的常见变应原,男女患者对卡巴混合物和芳香混合物的反应存在差异,斑贴试验对慢性湿疹寻找致敏原及日常防护具有重要意义。Objective：Investigating the results of the patch test of chronic eczema patients and the clinical significance of the test results.Methods： Patch test on the 835 confirmed chronic urticaria patients and process the results statistically.Results： The rate of positive result in patch test is 85.39%,and it shows no difference between genders and ages.The positive rate is higher among the patients with localized skin lesions than that among the patients with generalized lesions,but it has no statistical significance in this test.The five allergens,which show the highest rate of positive result,in order are Potassium dichromate,Nickle sulfate,Carba mix,Formaldehyde and Fragrance mix,and among which,the rate of Carba mix positive of male is obviously higher than that of female and the rate of Fragrance mix positive of female is much higher than that of male.In 41.55% of these cases,the patients had three or more positive allergens.Conclusion： Potassium dichromate,Nickle sulfate,Carba mix,Formaldehyde and Fragrance mix are common allergens of chronic eczema in local region;the reactions to Carba mix and Fragrance mix of male and female are different;and the patch test on confirming the allergens and indicating the daily protection of chronic eczema is important.

关 键 词：湿疹 斑贴试验 变应原 

分 类 号：R758.23[医药卫生—皮肤病学与性病学]