Synthesis and application of chiral N,N'-dialkylated cyclohexanediamine for asymmetric hydrogenation of aryl ketones  

作　　者：Meng Lin Ma Chuan Hong Ren Ya Jing Lv Hua Chen Xian Jun Li 

机构地区：[1]Department of Chemistry,Xihua University,Chengdu 610039,China [2]Key Lab of Green Chemistry and Technology,Ministry of Education,The Institute of Homogeneous Catalysis, Faculty of Chemistry,Sichuan University,Chengdu 610064,China

出　　处：《Chinese Chemical Letters》2011年第2期155-158,共4页中国化学快报（英文版）

基　　金：the NSFC(No.20272037);the NSF of Sichuan(No.07ZA109);the foundation of Xihua University(No. R0723315) and(No.XZD0912-09) for the financial support of this work

摘　　要：Chiral N,N＇-dialkylated cyclohexanediamine derived ligands have been synthesized and used in the asymmetric hydrogenation of aryl ketones.Optically active alcohols with up to 90%enantiomeric excess were obtained in high yields.Chiral N,N＇-dialkylated cyclohexanediamine derived ligands have been synthesized and used in the asymmetric hydrogenation of aryl ketones.Optically active alcohols with up to 90%enantiomeric excess were obtained in high yields.

关 键 词：Chiral diamine Aryl ketone Asymmetric hydrogenation Ruthenium complex 

分 类 号：TQ440.51[化学工程—化学肥料工业] O621.34[理学—有机化学]