Two new benzopyran derivatives from Gouania leptostachya DC. var. tonkinensis Pitard.  

作　　者：Chong Yao Shu Jie Zhang Zheng Zhong Bai Tong Zhou Li Jiang Xua 

机构地区：[1]Huzhou Central Hospital, Huzhou 313000, China [2]Heilongjiang University of Chinese Medicine, Harbin 150040, China [3]Heilongjiang Institute for Drug Control, Harbin 150001, China [4]State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai 201203, China Received 27 May 2010

出　　处：《Chinese Chemical Letters》2011年第2期175-177,共3页中国化学快报（英文版）

基　　金：the National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program",China(No.2009ZX09301-001)

摘　　要：Two new benzopyran derivatives,1-[（rel 2S,3R）-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone（1）,and 1-[（rel 25,35）-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone（2）,along with four known flavonoids,prodelphinidin C,prodelphinidin B3,（-）-epi-gallocatechin and（＋）-gallocatechin,were isolated from the stems of Gouania leptostachya DC.var. tonkinensis Pitard.Their structures were determined on the basis of spectroscopic methods including HR-ESI-MS,1D and 2D NMR.Prodelphinidin C exhibited significant inhibitory activity forα-glucosidase.Two new benzopyran derivatives,1-[（rel 2S,3R）-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone（1）,and 1-[（rel 25,35）-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone（2）,along with four known flavonoids,prodelphinidin C,prodelphinidin B3,（-）-epi-gallocatechin and（＋）-gallocatechin,were isolated from the stems of Gouania leptostachya DC.var. tonkinensis Pitard.Their structures were determined on the basis of spectroscopic methods including HR-ESI-MS,1D and 2D NMR.Prodelphinidin C exhibited significant inhibitory activity forα-glucosidase.

关 键 词：Gouania leptostachya DC.var.tonkinensis Pitard. Benzopyran derivatives α-Glucosidase inhibitory activity 

分 类 号：TQ463.54[化学工程—制药化工] S451.1[农业科学—植物保护]