Effect of dextran molecular weight on resonance light-scattering of quantum dots modified with dextran and concanavalin A  

作　　者：Shuang Hu Zhuo Bin Shan Yu Wang 

机构地区：[1]School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China [2]School of Pharmacy, Shanxi Medical University, Taiyuan 030001, China Received 2 June 2010

出　　处：《Chinese Chemical Letters》2011年第2期205-208,共4页中国化学快报（英文版）

基　　金：the Natural Science Foundation of Shanxi Province(No.2008011015-1) for financial support

摘　　要：The reversible aggregation between dextran-conjugated CdSe quantum dots（Dex-CdSe-QDs） and concanavalin A（Con A） was explored based on the specific affinity of polysaccharide for Con A by resonance light-scattering technique.In this study,the aggregation of Dex-CdSe-QDs induced by Con A and sequential dissociation by glucose was determined over a wide range of dextran molecular mass（10-500 kDa）.The results demonstrate that the sensitivity of lectin-dextran-modified-QDs interactions increase with dextran molecular mass,and an optimum dextran molecular mass is 500 kDa.The reversible aggregation between dextran-conjugated CdSe quantum dots（Dex-CdSe-QDs） and concanavalin A（Con A） was explored based on the specific affinity of polysaccharide for Con A by resonance light-scattering technique.In this study,the aggregation of Dex-CdSe-QDs induced by Con A and sequential dissociation by glucose was determined over a wide range of dextran molecular mass（10-500 kDa）.The results demonstrate that the sensitivity of lectin-dextran-modified-QDs interactions increase with dextran molecular mass,and an optimum dextran molecular mass is 500 kDa.

关 键 词：Dextran molecular mass CdSe quantum dots Concanavalin A Resonance light-scattering 

分 类 号：TQ464.1[化学工程—制药化工] TB383[一般工业技术—材料科学与工程]