双核素心肌显像和门控心肌灌注显像检测糖尿病心肌病的临床应用  

18F-FDG/99m Tc-MIBI Dual-Isotope SPECT and Gated Myocardial Imaging for Viability and Function Assessment of Diabetic Cardiomyopathy

作　　者：孙涛[1] 严金川[1] 陈小节[1] 梁仪[1] 赵建伟[1] 张朝普[1] 李璇[1] 

机构地区：[1]江苏大学附属医院心内科,江苏镇江212000

出　　处：《现代生物医学进展》2011年第1期87-89,共3页Progress in Modern Biomedicine

基　　金：江苏大学临床医学科技发展基金资助(JLY20080004)

摘　　要：目的:采用一日法静息99mTc-甲氧基异丁基异腈(MIBI)及18 F-脱氧葡萄糖(FDG)双核素同时采集(DISA)心肌灌注代谢显像与门控心肌灌注显像,评价糖尿病心肌病(DCM)患者心肌灌注、存活和心功能状况。方法:36例临床诊断为DCM患者,进行99mTc-MIBI和18F-FDG DISA灌注代谢显像及门控心肌灌注显像。结果:36例DISA显像中,26例为灌注/代谢不匹配型,提示心肌存活,10例为灌注代谢匹配型,提示心肌梗死,无存活心肌,心功能正常患者30例。结论:一日法DISA心肌灌注/代谢显像与门控法心肌灌注显像,可全面评价糖尿病心肌病患者的心肌灌注、存活及心功能状况。Objective： To investigate the diagnostic value of rest 99mTc-MIBI/18 F-FDG dual isotope simultaneous acquisition（DISA） and gated myocardial imaging for viability and function assessment of patients with diabetic cardiomyopathy（DCM）.Methods： Thirty-six patients of diabetic cardiomyopathy performed 18 F-FDG/99m Tc-MIBI DISA SPECT and gated myocardial imaging.Results： Among 36 DISA imagings,26 cases were perfusion /metabolism mismatched and suggested viable myocardium,while 10 cases were per-fusion /metabolism matched suggesting myocardium infarction.Conclusion： The same-day protocol of DISA and gated myocardial imag-ing study can well evaluate the myocardial viability and cardiac function for diabetic cardiomyopathy.

关 键 词：双核素同时采集 糖尿病心肌病 体层摄影术 发射型计算机 单光子 

分 类 号：R814.42[医药卫生—影像医学与核医学] R587.1[医药卫生—放射医学]