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作 者:张建[1]
出 处:《实用中西医结合临床》2011年第1期12-13,共2页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
摘 要:目的:探讨轻-中度支气管哮喘患者使用爱全乐合必可酮气雾剂吸入治疗4周以后,患者症状、体征及FEV1、PEF的改善情况。方法:以51例轻-中度支气管哮喘患者作为研究对象。治疗组25例使用爱全乐气雾剂吸入,每次2喷,4次/d,每4小时1次;同时合用必可酮气雾剂吸入,每次2喷,2次/d。对照组26例口服氨茶碱缓释片,每次0.1g,2次/d。结果:治疗组有效率88.0%,对照组有效率57.7%,差异有统计学意义(P<0.01)。治疗组FEV1、PEF总改善率均为96.0%,对照组FEV1总改善率76.9%,PEF总改善率73.1%,差异有统计学意义(P<0.05)。结论:轻-中度支气管哮喘患者存在多因素参与的气道炎症反应,笔者通过使用爱全乐合必可酮气雾剂联合吸入治疗,临床症状及体征的改善,FEV1、PEF总改善率均明显高于对照组,说明该疗法治疗效果好,缓解症状快,作用持久,副作用小,值得在临床推广使用。Objective:To evaluate the improvement on clinical characteristics,body features,FEV1 and PEF of patients with mild or moderate asthma who are under the treatment of atrovent and becotide for 4 weeks.Methods:25 Patients diagnosed with mild or moderate asthma were enrolled as study group and treated with atrovent,twice a time,four times a day,together with becotide,twice a time,twice a day.While 26 were enrolled as control group and treated with aminophylline sustained-release tablets,0.1 g a time,once every 12 hours.Results:88.0% of study group and only 57.7% of control group were improved,the difference is meaningful on statistics(P 0.01).96.0% of study group were improved on FEV1 and PEF,while in control group there were only 76.9% and 73.1%,and the difference is meaningful on statistics(P 0.05).Conclusions:There were different patterns of airways infammation in patients with mild or moderate asthma,based on the observation,it is obvious that patients treated with atrovent and becotide had much better improvements than those who are not treated so.Thus this treatment has very good,fast and lasting effects on mild or moderate asthma,and there are also less side effects,it is worthy commen using on clinic.
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