低蛋白饮食疗法对慢性肾小球肾炎导致的慢性肾衰竭患者肾功能进展的延缓效果  

Treatment effect of LPD on delaying the progress of renal function in patients with chronic renal failure resulting from CGN

作　　者：韩家强[1] 王金萍[2] 王琳[2] 

机构地区：[1]解放军第210医院干部二科 [2]大连大学附属新华医院内科,辽宁大连116021

出　　处：《临床军医杂志》2011年第1期33-34,共2页Clinical Journal of Medical Officers

摘　　要：目的探讨低蛋白饮食疗法对慢性肾小球肾炎(CGN)导致的慢性肾衰竭(CRF)患者肾功能进展的延缓效果。方法对54例CGN导致的CRF患者给予低蛋白饮食,通过检测24 h尿素氮排泄量计算实际蛋白质摄入量,观察不同的实际蛋白质摄入量对CRF进展的影响。结果实际蛋白质摄入量<0.7 g/(kg.d)者39例,CRF进展为(-0.09±0.20)ml/min/月;实际蛋白质摄入量>0.8 g/(kg.d)者15例,CRF进展为(-0.46±0.40)ml/min/月,两者比较,差异有统计学意义(P<0.01)。结论低蛋白饮食疗法确实可以延缓CGN导致的CRF患者肾功能的进展,但应严格控制实际蛋白质摄入量。Objective To discuss the treatment effect of LPD on delaying the progress of renal function in patients with chronic renal failure resulting from CGN.Methods 54 patients with chronic renal failure were given LPD.According to the detection of urea nitrogen excretion in 24h,calculate the actual protein intake and evaluate the effect with different protein intake.Results 39 cases actual protein intake[0.7g/（kg·d）],CRF progress（-0.09±0.20ml/min/month）;15 cases actual protein intake [0.8g /（kg·d）],CRF progress（-0.46±0.40ml/min/month）.There were significant differences between the two groups（P〈0.01）.Conclusion LPD has treatment effect of LPD on delaying the progress of renal function in patients with chronic renal failure resulting from CGN,but we must strictly control the actual protein intake.

关 键 词：慢性肾小球肾炎 慢性肾衰竭 低蛋白饮食 

分 类 号：R692.5[医药卫生—泌尿科学]