^1H-MRS磁共振波谱分析对海马硬化诊断的评价  

Evaluation of ^1H magnetic resonance spectroscopy in the diagnosis of hippocampai sclerosis

作　　者：罗超[1] 陈元媛[1] 赵林[1] 宋佳[1] 

机构地区：[1]解放军广州军区武汉总医院放射影像科,湖北武汉430070

出　　处：《临床军医杂志》2011年第1期117-119,共3页Clinical Journal of Medical Officers

摘　　要：目的分析原发性颞叶癫痫与海马硬化之间的关系,探讨磁共振波谱成像(1H-MRS)在海马硬化早期诊断中的应用价值。方法回顾性分析30例经手术证实的海马硬化患者的临床表现、1H-MRS资料,重点分析1H-MRS的NAA、Cr、Cho波峰特点。结果 1H-MRS发现异常28例(93%),2例在MRI及1H-MRS均未见异常。结论 1H-MRS可对海马硬化或伴有海马胶质细胞增生者进行早期诊断,提高了海马硬化诊断的敏感性。Objective To investigate the relationship between primary temporal lobe epilepsy and hippocampal sclerosis（HS）.Analysis the value of magnetic resonance spectroscopy（1H-MRS）in the diagnosis of HS.Methods Retrospectively analyzed the clinical symptoms、1H-MRS findings in thirty patients with pathology proved HS.The parameters of 1H-MRS included peak characteristics of NAA、Cr and Cho.Results Abnormal parameters were found in twenty-eight patients（93%） on 1H-MRS.No abnormality was found in two patients on MRI and 1H-MRS.Conclusion 1H-MRS is a sensitive method to diagnosing early HS and improving the sensitivity of HS.

关 键 词：癫痫 颞叶 海马硬化 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]